FD&C Yellow No. 5 Aluminum Lake
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MedKoo CAT#: 596146

CAS#: 12225-21-7

Description: FD&C Yellow No. 5 Aluminum Lake is a synthetic lemon yellow azo dye primarily used as a food coloring.


Chemical Structure

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FD&C Yellow No. 5 Aluminum Lake
CAS# 12225-21-7

Theoretical Analysis

MedKoo Cat#: 596146
Name: FD&C Yellow No. 5 Aluminum Lake
CAS#: 12225-21-7
Chemical Formula: C16H9N4Na3O9S2
Exact Mass: 533.95
Molecular Weight: 534.360
Elemental Analysis: C, 35.96; H, 1.70; N, 10.49; Na, 12.91; O, 26.95; S, 12.00

Price and Availability

Size Price Availability Quantity
25g USD 450 2 weeks
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Synonym: FD&C Yellow No. 5 Aluminum Lake; C.I. Food Yellow 4:1; Japan Food Yellow No. 4 aluminum lake; C.I. 19140:1; Pigment Yellow 100; EC 235-428-9;

IUPAC/Chemical Name: sodium (E)-5-oxo-1-(4-sulfonatophenyl)-4-((4-sulfonatophenyl)diazenyl)-4,5-dihydro-1H-pyrazole-3-carboxylate

InChi Key: UJMBCXLDXJUMFB-GLCFPVLVSA-K

InChi Code: InChI=1S/C16H12N4O9S2.3Na/c21-15-13(18-17-9-1-5-11(6-2-9)30(24,25)26)14(16(22)23)19-20(15)10-3-7-12(8-4-10)31(27,28)29;;;/h1-8,13H,(H,22,23)(H,24,25,26)(H,27,28,29);;;/q;3*+1/p-3/b18-17+;;;

SMILES Code: O=C1N(C2=CC=C(S(=O)([O-])=O)C=C2)N=C(C([O-])=O)C1/N=N/C3=CC=C(S(=O)([O-])=O)C=C3.[Na+].[Na+].[Na+]

Appearance: Solid powder

Purity: >95% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 3205.00.5010

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 534.36 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Songyang Y, Yang X, Xie S, Hao H, Song J. Highly-sensitive and rapid determination of sunset yellow using functionalized montmorillonite-modified electrode. Food Chem. 2015 Apr 15;173:640-4. doi: 10.1016/j.foodchem.2014.10.075. Epub 2014 Oct 22. PubMed PMID: 25466070.

2: Zhang Y, Chang C, Guo Q, Cao H, Bai Y, Liu H. [Analysis of tartrazine aluminum lake and sunset yellow aluminum lake in foods by capillary zone electrophoresis]. Se Pu. 2014 Apr;32(4):438-42. Chinese. PubMed PMID: 25069336.

3: Desai A, Peck GE, Lovell JE, White JL, Hem SL. The effect of aluminum hydroxide dissolution on the bleeding of aluminum lake dyes. Pharm Res. 1993 Oct;10(10):1458-60. PubMed PMID: 8272407.