Acetamiprid
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 591062

CAS#: 135410-20-7

Description: Acetamiprid is an organic compound with the chemical formula C10H11ClN4. It is an odorless neonicotinoid insecticide.

Chemical Structure

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Acetamiprid
CAS# 135410-20-7
Instruction

Theoretical Analysis

MedKoo Cat#: 591062
Name: Acetamiprid
CAS#: 135410-20-7
Chemical Formula: C10H11ClN4
Exact Mass: 222.07
Molecular Weight: 222.680
Elemental Analysis: C, 53.94; H, 4.98; Cl, 15.92; N, 25.16

Price and Availability

Size Price Availability Quantity
50mg USD 285 2 Weeks
100mg USD 500 2 Weeks
250mg USD 850 2 Weeks
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Synonym: Intruder; Mospilan; Mospilan; 20SP

IUPAC/Chemical Name: Ethanimidamide, N-((6-chloro-3-pyridinyl)methyl)-N'-cyano-N-methyl-, (E)-

InChi Key: WCXDHFDTOYPNIE-RIYZIHGNSA-N

InChi Code: InChI=1S/C10H11ClN4/c1-8(14-7-12)15(2)6-9-3-4-10(11)13-5-9/h3-5H,6H2,1-2H3/b14-8+

SMILES Code: C/C(N(CC1=CC=C(Cl)N=C1)C)=N\C#N

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 222.68 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Zhang Q, Wang X, Li Z, Jin H, Lu Z, Yu C, Huang YF, Zhao M. Simultaneous determination of nine neonicotinoids in human urine using isotope-dilution ultra-performance liquid chromatography-tandem mass spectrometry. Environ Pollut. 2018 May 14;240:647-652. doi: 10.1016/j.envpol.2018.04.144. [Epub ahead of print] PubMed PMID: 29772515.

2: Kachangoon R, Vichapong J, Burakham R, Santaladchaiyakit Y, Srijaranai S. Ultrasonically Modified Amended-Cloud Point Extraction for Simultaneous Pre-Concentration of Neonicotinoid Insecticide Residues. Molecules. 2018 May 12;23(5). pii: E1165. doi: 10.3390/molecules23051165. PubMed PMID: 29757232.

3: Francesena N, Schneider MI. Selectivity assessment of two biorational insecticides, azadirachtin and pyriproxyfen, in comparison to a neonicotinoid, acetamiprid, on pupae and adults of a Neotropical strain Eretmocerus mundus Mercet. Chemosphere. 2018 May 2;206:349-358. doi: 10.1016/j.chemosphere.2018.05.010. [Epub ahead of print] PubMed PMID: 29754059.

4: Feyereisen R. Toxicology: Bee P450s Take the Sting out of Cyanoamidine Neonicotinoids. Curr Biol. 2018 May 7;28(9):R560-R562. doi: 10.1016/j.cub.2018.03.013. PubMed PMID: 29738731.

5: Song S, Zhang C, Chen Z, He F, Wei J, Tan H, Li X. Simultaneous determination of neonicotinoid insecticides and insect growth regulators residues in honey using LC-MS/MS with anion exchanger-disposable pipette extraction. J Chromatogr A. 2018 May 3. pii: S0021-9673(18)30561-2. doi: 10.1016/j.chroma.2018.05.003. [Epub ahead of print] PubMed PMID: 29735281.

6: Marina CF, Bond JG, Muñoz J, Valle J, Quiroz-Martínez H, Torres-Monzón JA, Williams T. Efficacy of larvicides for the control of dengue, Zika, and chikungunya vectors in an urban cemetery in southern Mexico. Parasitol Res. 2018 Jun;117(6):1941-1952. doi: 10.1007/s00436-018-5891-x. Epub 2018 Apr 30. PubMed PMID: 29713901.

7: Hayat K, Afzal M, Aqueel MA, Ali S, Saeed MF, Khan QM, Ashfaq M, Damalas CA. Insecticide exposure affects DNA and antioxidant enzymes activity in honey bee species Apis florea and A. dorsata: Evidence from Punjab, Pakistan. Sci Total Environ. 2018 Apr 23;635:1292-1301. doi: 10.1016/j.scitotenv.2018.04.221. [Epub ahead of print] PubMed PMID: 29710582.

8: Bahreyni A, Yazdian-Robati R, Ramezani M, Abnous K, Taghdisi SM. Fluorometric aptasensing of the neonicotinoid insecticide acetamiprid by using multiple complementary strands and gold nanoparticles. Mikrochim Acta. 2018 Apr 29;185(5):272. doi: 10.1007/s00604-018-2805-7. PubMed PMID: 29705858.

9: Li B, Lin J, Pang X, Li H, Li X, Liu F, Mu W. Binary mixtures of alcohol ethoxylates, nonylphenol ethoxylates and pesticides exhibit comparative bioactivity against three pests and toxicological risks to aquatic organisms. Chemosphere. 2018 Aug;204:44-50. doi: 10.1016/j.chemosphere.2018.04.034. Epub 2018 Apr 7. PubMed PMID: 29649663.

10: Moyakao K, Santaladchaiyakit Y, Srijaranai S, Vichapong J. Preconcentration of Trace Neonicotinoid Insecticide Residues Using Vortex-Assisted Dispersive Micro Solid-Phase Extraction with Montmorillonite as an Efficient Sorbent. Molecules. 2018 Apr 11;23(4). pii: E883. doi: 10.3390/molecules23040883. PubMed PMID: 29641473.

11: Sun N, Ding Y, Tao Z, You H, Hua X, Wang M. Development of an upconversion fluorescence DNA probe for the detection of acetamiprid by magnetic nanoparticles separation. Food Chem. 2018 Aug 15;257:289-294. doi: 10.1016/j.foodchem.2018.02.148. Epub 2018 Mar 2. PubMed PMID: 29622212.

12: Şenyildiz M, Kilinc A, Ozden S. Investigation of the genotoxic and cytotoxic effects of widely used neonicotinoid insecticides in HepG2 and SH-SY5Y cells. Toxicol Ind Health. 2018 Jun;34(6):375-383. doi: 10.1177/0748233718762609. Epub 2018 Mar 28. PubMed PMID: 29591886.

13: Manjon C, Troczka BJ, Zaworra M, Beadle K, Randall E, Hertlein G, Singh KS, Zimmer CT, Homem RA, Lueke B, Reid R, Kor L, Kohler M, Benting J, Williamson MS, Davies TGE, Field LM, Bass C, Nauen R. Unravelling the Molecular Determinants of Bee Sensitivity to Neonicotinoid Insecticides. Curr Biol. 2018 Apr 2;28(7):1137-1143.e5. doi: 10.1016/j.cub.2018.02.045. Epub 2018 Mar 22. PubMed PMID: 29576476; PubMed Central PMCID: PMC5887109.

14: Kumar N, Narayanan N, Gupta S. Application of magnetic molecularly imprinted polymers for extraction of imidacloprid from eggplant and honey. Food Chem. 2018 Jul 30;255:81-88. doi: 10.1016/j.foodchem.2018.02.061. Epub 2018 Feb 12. PubMed PMID: 29571502.

15: Bartlett AJ, Hedges AM, Intini KD, Brown LR, Maisonneuve FJ, Robinson SA, Gillis PL, de Solla SR. Lethal and sublethal toxicity of neonicotinoid and butenolide insecticides to the mayfly, Hexagenia spp. Environ Pollut. 2018 Jul;238:63-75. doi: 10.1016/j.envpol.2018.03.004. Epub 2018 Mar 12. PubMed PMID: 29544197.

16: Çamlıca Y, Bediz SC, Çömelekoğlu Ü, Yilmaz ŞN. Toxic effect of acetamiprid on Rana ridibunda sciatic nerve (electrophysiological and histopathological potential). Drug Chem Toxicol. 2018 Mar 14:1-6. doi: 10.1080/01480545.2018.1442475. [Epub ahead of print] PubMed PMID: 29536770.

17: Zhou Y, Lu X, Fu X, Yu B, Wang D, Zhao C, Zhang Q, Tan Y, Wang X. Development of a fast and sensitive method for measuring multiple neonicotinoid insecticide residues in soil and the application in parks and residential areas. Anal Chim Acta. 2018 Aug 3;1016:19-28. doi: 10.1016/j.aca.2018.02.047. Epub 2018 Feb 20. PubMed PMID: 29534801.

18: Li Y, Long L, Yan H, Ge J, Cheng J, Ren L, Yu X. Comparison of uptake, translocation and accumulation of several neonicotinoids in komatsuna (Brassica rapa var. perviridis) from contaminated soils. Chemosphere. 2018 Jun;200:603-611. doi: 10.1016/j.chemosphere.2018.02.104. Epub 2018 Feb 20. PubMed PMID: 29510368.

19: Montiel-León JM, Duy SV, Munoz G, Amyot M, Sauvé S. Evaluation of on-line concentration coupled to liquid chromatography tandem mass spectrometry for the quantification of neonicotinoids and fipronil in surface water and tap water. Anal Bioanal Chem. 2018 Apr;410(11):2765-2779. doi: 10.1007/s00216-018-0957-2. Epub 2018 Mar 5. PubMed PMID: 29508034.

20: Bagri P, Jain SK. Assessment of acetamiprid-induced genotoxic effects in bone marrow cells of Swiss albino male mice. Drug Chem Toxicol. 2018 Feb 6:1-7. doi: 10.1080/01480545.2018.1429461. [Epub ahead of print] PubMed PMID: 29405074.