WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 596091
CAS#: 10173-01-0
Description: Jaceidin is an O-methylated flavonol. It can be found in Chamomilla recutita, and in Centaurea jacea.
MedKoo Cat#: 596091
Name: Jaceidin
CAS#: 10173-01-0
Chemical Formula: C18H16O8
Exact Mass: 360.0845
Molecular Weight: 360.31
Elemental Analysis: C, 60.00; H, 4.48; O, 35.52
This product is not in stock, which may be available by custom synthesis.
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Synonym: Jaceidin;
IUPAC/Chemical Name: 5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-3,6-dimethoxy-4H-chromen-4-one
InChi Key: XUWTZJRCCPNNJR-UHFFFAOYSA-N
InChi Code: InChI=1S/C18H16O8/c1-23-11-6-8(4-5-9(11)19)16-18(25-3)15(22)13-12(26-16)7-10(20)17(24-2)14(13)21/h4-7,19-21H,1-3H3
SMILES Code: O=C1C(OC)=C(C2=CC=C(O)C(OC)=C2)OC3=CC(O)=C(OC)C(O)=C13
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 360.31 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1: Allison BJ, Allenby MC, Bryant SS, Min JE, Hieromnimon M, Joyner PM. Antibacterial activity of fractions from three Chumash medicinal plant extracts and in vitro inhibition of the enzyme enoyl reductase by the flavonoid jaceosidin. Nat Prod Res. 2017 Mar;31(6):707-712. doi: 10.1080/14786419.2016.1217201. Epub 2016 Aug 2. PubMed PMID: 27482826.
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5: Aljancić I, Stanković M, Tesević V, Vujisić L, Vajs V, Milosavljević S. Protective effect on human lymphocytes of some flavonoids isolated from two Achillea species. Nat Prod Commun. 2010 May;5(5):729-32. PubMed PMID: 20521537.
6: Hussain J, Khan FU, Ur Rehman N, Ullah R, Mohmmad Z, Tasleem S, Naeem A, Shah MR. One new triterpene ester from Nepeta suavis. J Asian Nat Prod Res. 2009 Dec;11(12):997-1000. doi: 10.1080/10286020903264085. PubMed PMID: 20183267.
7: Afifi FU, Aburjai T. Antiplatelet activity of Varthemia iphionoides. Fitoterapia. 2004 Dec;75(7-8):629-33. PubMed PMID: 15567236.
8: Long C, Sauleau P, David B, Lavaud C, Cassabois V, Ausseil F, Massiot G. Bioactive flavonoids of Tanacetum parthenium revisited. Phytochemistry. 2003 Sep;64(2):567-9. PubMed PMID: 12943776.
9: Fukui K, Matsumoto T, Nakamura S, Nakayama M, Horie T. The synthesis of jaceidin. Experientia. 1968 Feb 15;24(2):108-9. PubMed PMID: 5643784.
