WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 596088
CAS#: 5532-23-0
Description: Jacozine is an alkaloid found in ragwort.
MedKoo Cat#: 596088
Name: Jacozine
CAS#: 5532-23-0
Chemical Formula: C18H23NO6
Exact Mass: 349.1525
Molecular Weight: 349.38
Elemental Analysis: C, 61.88; H, 6.64; N, 4.01; O, 27.48
Jacozine is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.
Synonym: Jacozine;
IUPAC/Chemical Name: (2S,3S,6'R,9a1'R,14a'R)-6'-hydroxy-3,6'-dimethyl-5'-methylene-5',6',9',9a1',11',13',14',14a'-octahydro-2'H-spiro[oxirane-2,3'-[1,6]dioxacyclododecino[2,3,4-gh]pyrrolizine]-2',7'(4'H)-dione
InChi Key: XCEPKQNOWNOSFH-CGPXFRKCSA-N
InChi Code: InChI=1S/C18H23NO6/c1-10-8-18(11(2)25-18)16(21)24-13-5-7-19-6-4-12(14(13)19)9-23-15(20)17(10,3)22/h4,11,13-14,22H,1,5-9H2,2-3H3/t11-,13+,14+,17+,18-/m0/s1
SMILES Code: O=C(O[C@]1([H])CCN2[C@]1([H])C(COC([C@@]3(O)C)=O)=CC2)[C@]4(O[C@H]4C)CC3=C
The following data is based on the product molecular weight 349.38 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
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8: Deinzer ML, Thomson PA, Burgett DM, Isaacson DL. Pyrrolizidine alkaloids: their occurrence in honey from tansy ragwort (Senecio jacobaea L.) Science. 1977 Feb 4;195(4277):497-9. PubMed PMID: 835011.