C 325

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 591032

CAS#: 6546-56-1

Description: C 325 is an aerosol bronchodilator antihistaminic.


Chemical Structure

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C 325
CAS# 6546-56-1

Theoretical Analysis

MedKoo Cat#: 591032
Name: C 325
CAS#: 6546-56-1
Chemical Formula: C20H26BrCL2N3O
Exact Mass: 475.0636
Molecular Weight: 475.25
Elemental Analysis: C, 50.55; H, 5.51; Br, 16.81; Cl, 14.92; N, 8.84; O, 3.37

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: C-325; C 325; C325

IUPAC/Chemical Name: 1,4-Butanediamine, N'-(3-bromo-5-methoxy-9-acridinyl)-N,N-dimethyl-, dihydrochloride

InChi Key: RJSRKSRHGMYLGP-UHFFFAOYSA-N

InChi Code: InChI=1S/C20H24BrN3O.2ClH/c1-24(2)12-5-4-11-22-19-15-10-9-14(21)13-17(15)23-20-16(19)7-6-8-18(20)25-3;;/h6-10,13H,4-5,11-12H2,1-3H3,(H,22,23);2*1H

SMILES Code: CN(C)CCCCNC1=C(C=CC(Br)=C2)C2=NC3=C(OC)C=CC=C31.[H]Cl.[H]Cl

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 475.25 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Chang HS, Park SH, Cho KM, Kim JW. Plugger temperature of cordless heat carriers according to the time elapsed. Restor Dent Endod. 2018 Feb 7;43(1):e12. doi: 10.5395/rde.2018.43.e12. eCollection 2018 Feb. PubMed PMID: 29487842; PubMed Central PMCID: PMC5816989.

2: Cowgill LD, Polzin DJ, Elliott J, Nabity MB, Segev G, Grauer GF, Brown S, Langston C, van Dongen AM. Is Progressive Chronic Kidney Disease a Slow Acute Kidney Injury? Vet Clin North Am Small Anim Pract. 2016 Nov;46(6):995-1013. doi: 10.1016/j.cvsm.2016.06.001. Review. PubMed PMID: 27593574.

3: Zhao X, Gu Y, Du X, Shao M, Luo H, Zhu L, Zhou Q, Zhang G. [Analysis of ATP2A2 gene mutations in a pedigree and a sporadic case with Darier disease]. Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2016 Oct;33(5):641-4. doi: 10.3760/cma.j.issn.1003-9406.2016.05.013. Chinese. PubMed PMID: 27577212.

4: Chen XL, Geng CA, Chen JJ. A Fragmentation Study of Six C21 Steroidal Aglycones by Electrospray Ionization Ion-Trap Time-of-Flight Tandem Mass Spectrometry. Nat Prod Commun. 2015 Dec;10(12):2053-8. PubMed PMID: 26882663.

5: Pugh T, Cosham SD, Hamilton JA, Kingsley AJ, Johnson AL. Cobalt(III) diazabutadiene precursors for metal deposition: nanoparticle and thin film growth. Inorg Chem. 2013 Dec 2;52(23):13719-29. doi: 10.1021/ic402317g. Epub 2013 Nov 15. PubMed PMID: 24236689.

6: An Y, Lou Y, Xu Y. Overexpression, crystallization and preliminary X-ray crystallographic analysis of release factor eRF1-1 from Arabidopsis thaliana. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Nov;69(Pt 11):1295-8. doi: 10.1107/S1744309113027784. Epub 2013 Oct 30. PubMed PMID: 24192373; PubMed Central PMCID: PMC3818057.

7: Iyer SN, Ankala A, Singhal RS, Hegde MR. Determination of common genetic variants in cytidine deaminase (CDA) gene in Indian ethnic population. Gene. 2013 Jul 15;524(1):35-9. doi: 10.1016/j.gene.2013.04.015. Epub 2013 Apr 21. PubMed PMID: 23612254.

8: Gurbel PA, Bliden KP, Fort J, Zhang Y, Plachetka JR, Antonino M, Gesheff M, Tantry US. Pharmacodynamic evaluation of clopidogrel plus PA32540: the Spaced PA32540 With Clopidogrel Interaction Gauging (SPACING) study. Clin Pharmacol Ther. 2011 Dec;90(6):860-6. doi: 10.1038/clpt.2011.201. Epub 2011 Nov 2. PubMed PMID: 22048221.

9: Pérez-Elvira SI, Ferreira LC, Donoso-Bravo A, Fdz-Polanco M, Fdz-Polanco F. Full-stream and part-stream ultrasound treatment effect on sludge anaerobic digestion. Water Sci Technol. 2010;61(6):1363-72. doi: 10.2166/wst.2010.893. PubMed PMID: 20351414.

10: Del Gobbo L, Tittlemier S, Diamond M, Pepper K, Tague B, Yeudall F, Vanderlinden L. Cooking decreases observed perfluorinated compound concentrations in fish. J Agric Food Chem. 2008 Aug 27;56(16):7551-9. doi: 10.1021/jf800827r. Epub 2008 Jul 12. PubMed PMID: 18620413.

11: Byers HL, Tarelli E, Homer KA, Beighton D. Isolation and characterisation of sialidase from a strain of Streptococcus oralis. J Med Microbiol. 2000 Mar;49(3):235-44. PubMed PMID: 10707943.

12: Vasson MP, Farges MC, Sarret A, Cynober L. Free amino acid concentrations in milk: effects of microwave versus conventional heating. Amino Acids. 1998;15(4):385-8. PubMed PMID: 9891762.

13: Fisher AJ, McKinney BR, Schneemann A, Rueckert RR, Johnson JE. Crystallization of viruslike particles assembled from flock house virus coat protein expressed in a baculovirus system. J Virol. 1993 May;67(5):2950-3. PubMed PMID: 8474184; PubMed Central PMCID: PMC237625.

14: Inoue M, Hayashi M, Sugimoto M, Harada S, Kai Y, Kasai N, Terada K, Izui K. First crystallization of a phosphoenolpyruvate carboxylase from Escherichia coli. J Mol Biol. 1989 Aug 5;208(3):509-10. PubMed PMID: 2677392.

15: Hsieh JH, Baldwin RE. Storage and microwave reheating effects on lipid oxidation of roast beef. J Microw Power. 1984 Sep;19(3):187-94. PubMed PMID: 6567670.

16: Drew F, Rhee KS, Carpenter ZL. Cooking at variable microwave power levels. Effects on energy use and quality of top round beef roasts. J Am Diet Assoc. 1980 Oct;77(4):455-9. PubMed PMID: 7419839.

17: Neukirch F, Korobaeff M, Verdier F, Timsit G, Fay M, Drutel P. [Effect of a histamine aerosol in 20 subjects with histamine hyperreactivity. Application to a study of the protective properties of pipoxizine]. Rev Inst Hyg Mines (Hasselt). 1978;33(4):191-5. French. PubMed PMID: 45187.

18: Minette A, Marcq M, Bruninx M. [Preliminary results of a trial on the spirometric and associated effects of a new bronchodilator, C 325 (author's transl)]. Acta Tuberc Pneumol Belg. 1974 Sep-Oct;65(5):520-33. French. PubMed PMID: 4466343.