WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 555254

CAS#: 947018-15-7

Description: J9 is a Glucocorticoid resistance inhibitor. J9 Reverses Dexamethasone Resistance in T-cell Acute Lymphoblastic Leukemia (T-ALL).

Chemical Structure

CAS# 947018-15-7

Theoretical Analysis

MedKoo Cat#: 555254
Name: J9
CAS#: 947018-15-7
Chemical Formula: C12H12N4
Exact Mass: 212.1062
Molecular Weight: 212.256
Elemental Analysis: C, 67.90; H, 5.70; N, 26.40

Price and Availability

Size Price Availability Quantity
1.0g USD 2950.0 2 Weeks
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Synonym: J9; J 9; J-9.

IUPAC/Chemical Name: 4-cyclopropyl-5-(pyridin-4-yl)pyrimidin-2-amine


InChi Code: InChI=1S/C12H12N4/c13-12-15-7-10(8-3-5-14-6-4-8)11(16-12)9-1-2-9/h3-7,9H,1-2H2,(H2,13,15,16)


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 212.256 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Cantley AM, Welsch M, Ambesi-Impiombato A, Sanchez-Martin M, Kim MY, Bauer A,
Ferrando A, Stockwell BR. Small Molecule that Reverses Dexamethasone Resistance
in T-cell Acute Lymphoblastic Leukemia (T-ALL). ACS Med Chem Lett. 2014 Apr
25;5(7):754-9. doi: 10.1021/ml500044g. eCollection 2014 Jul 10. PubMed PMID:
25050160; PubMed Central PMCID: PMC4094258.


1.0g / USD 2950.0