1-Tetralol, (S)-
featured

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 596048

CAS#: 53732-47-1

Description: 1-Tetralol, (S)- is a bioactive chemical.


Chemical Structure

img
1-Tetralol, (S)-
CAS# 53732-47-1

Theoretical Analysis

MedKoo Cat#: 596048
Name: 1-Tetralol, (S)-
CAS#: 53732-47-1
Chemical Formula: C10H12O
Exact Mass: 148.09
Molecular Weight: 148.200
Elemental Analysis: C, 81.04; H, 8.16; O, 10.80

Price and Availability

Size Price Availability Quantity
100mg USD 260 2 Weeks
Bulk inquiry

Synonym: 1-Tetralol, (S)-; (S)-Tetralin-1-ol; J330.337C; (S)-1-Hydroxytetralin;

IUPAC/Chemical Name: (S)-1,2,3,4-tetrahydronaphthalen-1-ol

InChi Key: JAAJQSRLGAYGKZ-JTQLQIEISA-N

InChi Code: InChI=1S/C10H12O/c11-10-7-3-5-8-4-1-2-6-9(8)10/h1-2,4,6,10-11H,3,5,7H2/t10-/m0/s1

SMILES Code: O[C@H]1CCCC2=C1C=CC=C2

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 148.20 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

1: Świzdor A, Janeczko T, Dmochowska-Gładysz J. Didymosphaeria igniaria: a new microorganism useful for the enantioselective reduction of aryl-aliphatic ketones. J Ind Microbiol Biotechnol. 2010 Nov;37(11):1121-30. doi: 10.1007/s10295-010-0759-9. Epub 2010 Jun 11. PubMed PMID: 20544255.

2: Penick MA, Mahindaratne MP, Gutierrez RD, Smith TD, Tiekink ER, Negrete GR. Tandem Friedel-Crafts annulation to novel perylene analogues. J Org Chem. 2008 Aug 15;73(16):6378-81. doi: 10.1021/jo800558c. Epub 2008 Jul 16. PubMed PMID: 18630879; PubMed Central PMCID: PMC4780845.

3: Bichlmaier I, Siiskonen A, Kurkela M, Finel M, Yli-Kauhaluoma J. Chiral distinction between the enantiomers of bicyclic alcohols by UDP-glucuronosyltransferases 2B7 and 2B17. Biol Chem. 2006 Apr;387(4):407-16. PubMed PMID: 16606339.

4: Gee CL, Tyndall JD, Grunewald GL, Wu Q, McLeish MJ, Martin JL. Mode of binding of methyl acceptor substrates to the adrenaline-synthesizing enzyme phenylethanolamine N-methyltransferase: implications for catalysis. Biochemistry. 2005 Dec 27;44(51):16875-85. PubMed PMID: 16363801.

5: Fujio M, Keeffe JR, More O'Ferrall RA, O'Donoghue AC. Unexpectedly small ortho-oxygen substituent effects on stabilities of benzylic carbocations. J Am Chem Soc. 2004 Aug 18;126(32):9982-92. PubMed PMID: 15303872.

6: Jung JC, Kim JC, Park OS, Jang BS. Synthesis of 4-hydroxy-1-thiocoumarin derivatives-1: an efficient synthesis of thioflocoumafen. Arch Pharm Res. 1999 Jun;22(3):302-5. PubMed PMID: 10403135.

7: Grayson DA, Tewari YB, Mayhew MP, Vilker VL, Goldberg RN. Tetralin as a substrate for camphor (cytochrome P450) 5-monooxygenase. Arch Biochem Biophys. 1996 Aug 15;332(2):239-47. PubMed PMID: 8806731.

8: Grunewald GL, Ye Q, Sall DJ, Criscione KR, Wise B. Conformational and steric aspects of phenylethanolamine and phenylethylamine analogues as substrates or inhibitors of phenylethanolamine N-methyltransferase. Mol Pharmacol. 1989 Jan;35(1):93-7. PubMed PMID: 2913486.

9: Grunewald GL, Ye QH. Stereochemical aspects of phenylethanolamine analogues as substrates of phenylethanolamine N-methyltransferase. J Med Chem. 1988 Oct;31(10):1984-6. PubMed PMID: 3172133.

10: Matos FF, Lippman DA, Malone MH. Opioid receptor effects of two 3-amino-2,2-dimethyltetralin analogs in guinea pig ileum longitudinal muscle. NIDA Res Monogr. 1986;75:217-9. PubMed PMID: 3123938.