WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 596013

CAS#: 701980-31-6

Description: J-78 is a bioactive chemical.

Chemical Structure

CAS# 701980-31-6

Theoretical Analysis

MedKoo Cat#: 596013
Name: J-78
CAS#: 701980-31-6
Chemical Formula: C16H8BrClFNO3
Exact Mass: 394.936
Molecular Weight: 396.59
Elemental Analysis: C, 48.46; H, 2.03; Br, 20.15; Cl, 8.94; F, 4.79; N, 3.53; O, 12.10

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: J-78; J78; J 78; UNII-154650W0UB;

IUPAC/Chemical Name: 2-((2-bromo-4-fluorophenyl)amino)-3-chloro-5-hydroxynaphthalene-1,4-dione


InChi Code: InChI=1S/C16H8BrClFNO3/c17-9-6-7(19)4-5-10(9)20-14-13(18)16(23)12-8(15(14)22)2-1-3-11(12)21/h1-6,20-21H

SMILES Code: O=C1C(NC2=CC=C(F)C=C2Br)=C(Cl)C(C3=C1C=CC=C3O)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 396.59 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.


Dilution Calculator

Calculate the dilution required to prepare a stock solution.

1: Bucher T, van der Horst K, Siegrist M. Fruit for dessert. How people compose
healthier meals. Appetite. 2013 Jan;60(1):74-80. doi:
10.1016/j.appet.2012.10.003. Epub 2012 Oct 16. PubMed PMID: 23085475.

2: Zhu J, Crossan P. SU-E-J-78: Enhance Patient Positioning Accuracy with
Optically Guided Frameless Target Localization Technique for Intracranial
Radiation Therapy. Med Phys. 2012 Jun;39(6Part7):3670. doi: 10.1118/1.4734913.
PubMed PMID: 28519781.

3: Bucher T, van der Horst K, Siegrist M. The fake food buffet - a new method in
nutrition behaviour research. Br J Nutr. 2012 May;107(10):1553-60. doi:
10.1017/S000711451100465X. Epub 2011 Sep 16. PubMed PMID: 21920063.

4: Dzhagan V, Lokteva I, Himcinschi C, Jin X, Kolny-Olesiak J, Zahn DR. Phonon
Raman spectra of colloidal CdTe nanocrystals: effect of size, non-stoichiometry
and ligand exchange. Nanoscale Res Lett. 2011 Jan 12;6(1):79. doi:
10.1186/1556-276X-6-79. PubMed PMID: 21711581; PubMed Central PMCID: PMC3212227.

5: Aliev MK, Tikhonov AN. Obstructed metabolite diffusion within skeletal muscle
cells in silico. Mol Cell Biochem. 2011 Dec;358(1-2):105-19. doi:
10.1007/s11010-011-0926-y. Epub 2011 Jun 28. PubMed PMID: 21710299.

6: Taylor B, Greenman J. Modelling the effects of pH on tongue biofilm using a
sorbarod biofilm perfusion system. J Breath Res. 2010 Mar;4(1):017107. doi:
10.1088/1752-7155/4/1/017107. Epub 2010 Mar 2. PubMed PMID: 21386212.

7: Huang X, Schwenke DW, Lee TJ. Rovibrational spectra of ammonia. I.
Unprecedented accuracy of a potential energy surface used with nonadiabatic
corrections. J Chem Phys. 2011 Jan 28;134(4):044320. doi: 10.1063/1.3541351.
PubMed PMID: 21280738.

8: Harding SE, Schuck P, Abdelhameed AS, Adams G, Kök MS, Morris GA. Extended
Fujita approach to the molecular weight distribution of polysaccharides and other
polymeric systems. Methods. 2011 May;54(1):136-44. doi:
10.1016/j.ymeth.2011.01.009. Epub 2011 Jan 27. PubMed PMID: 21276851; PubMed
Central PMCID: PMC3480191.

9: Wissler EH, Havenith G. A simple theoretical model of heat and moisture
transport in multi-layer garments in cool ambient air. Eur J Appl Physiol. 2009
Mar;105(5):797-808. doi: 10.1007/s00421-008-0966-5. Epub 2009 Jan 6. PubMed PMID:

10: Kundu T, Lee JP, Blase C, Bereiter-Hahn J. Acoustic microscope lens modeling
and its application in determining biological cell properties from single- and
multi-layered cell models. J Acoust Soc Am. 2006 Sep;120(3):1646-54. PubMed PMID:

11: Thomson NH. The substructure of immunoglobulin G resolved to 25 kDa using
amplitude modulation AFM in air. Ultramicroscopy. 2005 Nov;105(1-4):103-10. Epub
2005 Jul 13. PubMed PMID: 16051439.

12: Zhang Y, Ramabadran RS, Boddicker KA, Bawaney I, Davies LR, Zimmerman MB,
Wuthrich S, Jones JL, Kerber RE. Triphasic waveforms are superior to biphasic
waveforms for transthoracic defibrillation: experimental studies. J Am Coll
Cardiol. 2003 Aug 6;42(3):568-75. PubMed PMID: 12906990.

13: Joubert AM, Byrd AS, LiCata VJ. Global conformations, hydrodynamics, and
X-ray scattering properties of Taq and Escherichia coli DNA polymerases in
solution. J Biol Chem. 2003 Jul 11;278(28):25341-7. Epub 2003 May 3. PubMed PMID:

14: Perugini MA, Schuck P, Howlett GJ. Differences in the binding capacity of
human apolipoprotein E3 and E4 to size-fractionated lipid emulsions. Eur J
Biochem. 2002 Dec;269(23):5939-49. PubMed PMID: 12444983.

15: Iwamoto M, Sudo Y, Shimono K, Kamo N. Illumination accelerates the decay of
the O-intermediate of pharaonis phoborhodopsin (sensory rhodopsin II). Photochem
Photobiol. 2002 Oct;76(4):462-6. PubMed PMID: 12405157.

16: Stevenson K, Hughes VM, de Juan L, Inglis NF, Wright F, Sharp JM. Molecular
characterization of pigmented and nonpigmented isolates of Mycobacterium avium
subsp. paratuberculosis. J Clin Microbiol. 2002 May;40(5):1798-804. PubMed PMID:
11980962; PubMed Central PMCID: PMC130953.

17: Bernèche S, Roux B. The ionization state and the conformation of Glu-71 in
the KcsA K(+) channel. Biophys J. 2002 Feb;82(2):772-80. PubMed PMID: 11806919;
PubMed Central PMCID: PMC1301886.

18: Gunthorpe MJ, Lummis SC. Conversion of the ion selectivity of the 5-HT(3a)
receptor from cationic to anionic reveals a conserved feature of the ligand-gated
ion channel superfamily. J Biol Chem. 2001 Jun 15;276(24):10977-83. PubMed PMID:

19: Tsuji A, Sato Y, Hirano M, Suga T, Koshimoto H, Taguchi T, Ohsuka S.
Development of a time-resolved fluorometric method for observing hybridization in
living cells using fluorescence resonance energy transfer. Biophys J. 2001
Jul;81(1):501-15. PubMed PMID: 11423432; PubMed Central PMCID: PMC1301529.

20: Murzyn K, Róg T, Jezierski G, Takaoka Y, Pasenkiewicz-Gierula M. Effects of
phospholipid unsaturation on the membrane/water interface: a molecular simulation
study. Biophys J. 2001 Jul;81(1):170-83. PubMed PMID: 11423404; PubMed Central
PMCID: PMC1301501.