Acetarsone
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 571547

CAS#: 97-44-9

Description: Acetarsone is an antifective agent that inhibits protozoa growth.


Chemical Structure

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Acetarsone
CAS# 97-44-9

Theoretical Analysis

MedKoo Cat#: 571547
Name: Acetarsone
CAS#: 97-44-9
Chemical Formula: C8H10AsNO5
Exact Mass: 274.9775
Molecular Weight: 275.09
Elemental Analysis: C, 34.93; H, 3.66; As, 27.24; N, 5.09; O, 29.08

Price and Availability

Size Price Availability Quantity
50.0g USD 290.0 2 Weeks
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Synonym: Amarsan; Amoebal; Osarsol; Vagisept; NSC 13160; NSC-13160; NSC13160.

IUPAC/Chemical Name: m-Arsanilic acid, N-acetyl-4-hydroxy-

InChi Key: ODFJOVXVLFUVNQ-UHFFFAOYSA-N

InChi Code: InChI=1S/C8H10AsNO5/c1-5(11)10-7-4-6(9(13,14)15)2-3-8(7)12/h2-4,12H,1H3,(H,10,11)(H2,13,14,15)

SMILES Code: O[As](O)(C1=CC=C(O)C(NC(C)=O)=C1)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 275.09 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Bayse GS, Hammonds-Odie LP, Jackson KM, Tucker DK, Kirlin WG. Permeation of roxarsone and its metabolites increases caco-2 cell proliferation. Adv Biol Chem. 2013 Aug;3(4):389-396. PubMed PMID: 25632371; PubMed Central PMCID: PMC4306191.

2: Olavarría-Fullerton J, Wells S, Ortiz-Rivera W, Sepaniak MJ, De Jesús MA. Surface-enhanced Raman scattering (SERS) characterization of trace organoarsenic antimicrobials using silver/polydimethylsiloxane nanocomposites. Appl Spectrosc. 2011 Apr;65(4):423-8. doi: 10.1366/10-06116. PubMed PMID: 21396190.

3: Sasseville D, Carey WD, Singer MI. Generalized contact dermatitis from acetarsone. Contact Dermatitis. 1995 Dec;33(6):431-2. PubMed PMID: 8706406.

4: Hiskey CF, Cantwell FF. Ultraviolet spectrum correlations with the conjugate acid-base species of acetarsone and arsthinol. J Pharm Sci. 1968 Dec;57(12):2105-11. PubMed PMID: 5708352.

5: WHITE A. Acute systemic reaction to acetarsol. Br Med J. 1956 Dec 29;2(5008):1528-9. PubMed PMID: 13374373; PubMed Central PMCID: PMC2036064.

6: SHVARTSVASSER IP, VAINGRIB LG. [Acute hemorrhagic encephalitis following intake of osarsol]. Sov Med. 1956 May;20(5):76-7. Russian. PubMed PMID: 13351919.

7: OEHNINGER C, RODRIGUEZ BARRIOS R, GOMEZ HAEDO CA. Optic neuritis caused by arsenicals; treatment with B.A.L. Br J Ophthalmol. 1955 Jul;39(7):422-8. PubMed PMID: 13240036; PubMed Central PMCID: PMC1324567.

8: BASCH. [Treatment of recurrent trichomonal vulvovaginitis by local applications of sodium stovarsol]. C R Soc Fr Gyncol. 1955 May-Sep;25(5):220-1. French. PubMed PMID: 13261526.

9: LEBON J, MESSERSCHMITT J. [Drug-induced aplastic myelosis; terminal acute myeloblstosis; pathogenic reflections]. Sang. 1955;26(8):799-804. French. PubMed PMID: 13337079.

10: BIERICH JR. [Spirocid encephalitis]. Arch Kinderheilkd. 1955;151(1):5-19. German. PubMed PMID: 13259600.

11: PECK BJ. Exfoliative dermatitis after acetarsol vaginal pessaries. Br Med J. 1954 Oct 9;2(4892):850-1. PubMed PMID: 13199327; PubMed Central PMCID: PMC2079486.

12: ANDRE L, MARTY J, RISPE R, MORICHAU-BEAUCHANT J. [Lymphoid leukemia in a syphilitic treated with sodium stovarsol and with bismuth]. Bull Mem Soc Med Hop Paris. 1954 May 14-21;70(15-16):540-3. French. PubMed PMID: 13190396.

13: JEDLICKA J. [Sarcoidosis pulmonum; a contribution to the chemotherapy of Besnier-Boeck-Schaumann disease. II. Report]. Sb Lek. 1954 Apr;56(4):73-8. Czech. PubMed PMID: 13237896.

14: KOSTIC P, GRUBAC M. [Not Available]. Med Glas. 1954 Mar-Apr;8(3-4):120-5. Undetermined Language. PubMed PMID: 13193381.

15: WATTLEY GH. The treatment of stovarsol-resistant balantidiasis with aureomycin; a case report. Caribb Med J. 1953;15(3-4):92-4. PubMed PMID: 13141256.

16: McCAREY AG. Balantidiasis in South Persia. Br Med J. 1952 Mar 22;1(4759):629-31. PubMed PMID: 14905008; PubMed Central PMCID: PMC2023172.

17: SONNECK HJ. [Erythematosus discoides chronicus with exacerbation by spirocid]. Dtsch Gesundheitsw. 1952 Feb 21;7(8):239-44. Undetermined Language. PubMed PMID: 14936556.

18: POPOVIC S. [Treatment of a case of poisoning with stovarsol with BAL]. Med Arh. 1952 Jan-Feb;6(1):55-62. Undetermined Language. PubMed PMID: 14947473.

19: OULES J, ALLAIX D. [Experimental stovarsol therapy of manic crises]. Ann Med Psychol (Paris). 1952 Jan;110(1 1):86-8. Undetermined Language. PubMed PMID: 14944008.

20: ORCHARD WE. Dermatitis after use of pentavalent arsenicals per vaginam. Br Med J. 1951 Dec 15;2(4745):1444. PubMed PMID: 14879130; PubMed Central PMCID: PMC2070664.