WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 341487
CAS#: 3530-56-1
Description: Xylocytidine is a biochemical.
MedKoo Cat#: 341487
Name: Xylocytidine
CAS#: 3530-56-1
Chemical Formula: C9H13N3O5
Exact Mass: 243.0855
Molecular Weight: 243.219
Elemental Analysis: C, 44.45; H, 5.39; N, 17.28; O, 32.89
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
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Synonym: Xylocytidine;
IUPAC/Chemical Name: 2(1H)-Pyrimidinone, 4-amino-1-beta-D-xylofuranosyl-
InChi Key: UHDGCWIWMRVCDJ-PXBUCIJWSA-N
InChi Code: InChI=1S/C9H13N3O5/c10-5-1-2-12(9(16)11-5)8-7(15)6(14)4(3-13)17-8/h1-2,4,6-8,13-15H,3H2,(H2,10,11,16)/t4-,6+,7-,8-/m1/s1
SMILES Code: O=C1N=C(N)C=CN1[C@H]2[C@@H]([C@H]([C@@H](CO)O2)O)O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 243.219 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1: Ham YM, Choi KJ, Song SY, Jin YH, Chun MW, Lee SK. Xylocydine, a novel inhibitor of cyclin-dependent kinases, prevents the tumor necrosis factor-related apoptosis-inducing ligand-induced apoptotic cell death of SK-HEP-1 cells. J Pharmacol Exp Ther. 2004 Mar;308(3):814-9. Epub 2003 Nov 14. PubMed PMID: 14617691.
2: Mirzayans R, Cubitt S, Enns L, Karimian K, Radatus B, Hirani-Hojatti S, Murthy K, Paterson MC. Comparative genotoxicity of 2,3'-O-cyclocytidine, beta-xylocytidine and 1-beta-D-arabinofuranosylcytosine in human tumor cell lines. Carcinogenesis. 1994 Oct;15(10):2319-24. PubMed PMID: 7525096.
