Xylazine hydrochloride

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 341476

CAS#: 23076-35-9 (HCl)

Description: Xylazine is an analogue of clonidine and an agonist at the α2 class of adrenergic receptor. It is used for sedation, anesthesia, muscle relaxation, and analgesia in animals such as horses, cattle and other non-human mammals. Veterinarians also use xylazine as an emetic, especially in cats.

Chemical Structure

Xylazine hydrochloride
CAS# 23076-35-9 (HCl)

Theoretical Analysis

MedKoo Cat#: 341476
Name: Xylazine hydrochloride
CAS#: 23076-35-9 (HCl)
Chemical Formula: C12H17ClN2S
Exact Mass: 256.08
Molecular Weight: 256.792
Elemental Analysis: C, 56.13; H, 6.67; Cl, 13.80; N, 10.91; S, 12.48

Price and Availability

Size Price Availability Quantity
5g USD 450
10g USD 650
25g USD 950
100g USD 1950
1kg USD 5950
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Related CAS #: 23076-35-9 (HCl)   7361-61-7 (free base)    

Synonym: Xylazine hydrochloride; BAY-VA 1470; Anased; BAY 1470; BAY1470; BAY-1470; Primazine; Rometar; Sedomin; WH 7286; Xilazina

IUPAC/Chemical Name: 4H-1,3-Thiazin-2-amine, N-(2,6-dimethylphenyl)-5,6-dihydro-, monohydrochloride


InChi Code: InChI=1S/C12H16N2S.ClH/c1-9-5-3-6-10(2)11(9)14-12-13-7-4-8-15-12;/h3,5-6H,4,7-8H2,1-2H3,(H,13,14);1H


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 256.79 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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10: Ida KK, Sauvage A, Gougnard A, Grauwels M, Serteyn D, Sandersen C. Use of Nasotracheal Intubation during General Anesthesia in Two Ponies with Tracheal Collapse. Front Vet Sci. 2018 Mar 13;5:42. doi: 10.3389/fvets.2018.00042. eCollection 2018. PubMed PMID: 29594157; PubMed Central PMCID: PMC5859214.

11: Haan JD, Hay Kraus BL, Sathe SR. A comparison of the effects of carbon dioxide and medical air for abdominal insufflation on respiratory parameters in xylazine-sedated sheep undergoing laparoscopic artificial insemination. N Z Vet J. 2018 Apr 25:1-5. doi: 10.1080/00480169.2018.1458661. [Epub ahead of print] PubMed PMID: 29591780.

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13: Sahu S, Li R, Kadeyala PK, Liu S, Schachner M. The human natural killer-1 (HNK-1) glycan mimetic ursolic acid promotes functional recovery after spinal cord injury in mouse. J Nutr Biochem. 2018 Feb 9;55:219-228. doi: 10.1016/j.jnutbio.2018.01.016. [Epub ahead of print] PubMed PMID: 29567576.


15: Hibbs CD, Barrett PM, Dees DD. Intraocular pressure reference intervals in eyes of clinically normal miniature donkeys (Equus africanus asinus). Vet Ophthalmol. 2018 Mar 8. doi: 10.1111/vop.12561. [Epub ahead of print] PubMed PMID: 29517162.

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20: Wittenberg-Voges L, Kästner SB, Raekallio M, Vainio OM, Rohn K, Hopster K. Effect of dexmedetomidine and xylazine followed by MK-467 on gastrointestinal microperfusion in anaesthetized horses. Vet Anaesth Analg. 2018 Mar;45(2):165-174. doi: 10.1016/j.vaa.2017.08.010. Epub 2017 Sep 15. PubMed PMID: 29439859.