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MedKoo CAT#: 341475

CAS#: 6443-50-1

Description: Xylamidine is a biochemical.

Price and Availability

Size Price Shipping out time Quantity
Inquire bulk and customized quantity

Pricing updated 2020-07-14. Prices are subject to change without notice.

Xylamidine is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 341475
Name: Xylamidine
CAS#: 6443-50-1
Chemical Formula: C19H24N2O2
Exact Mass: 312.1838
Molecular Weight: 312.413
Elemental Analysis: C, 73.05; H, 7.74; N, 8.97; O, 10.24

Synonym: Xylamidine;

IUPAC/Chemical Name: Benzeneethanimidamide, N-(2-(3-methoxyphenoxy)propyl)-3-methyl-


InChi Code: InChI=1S/C19H24N2O2/c1-14-6-4-7-16(10-14)11-19(20)21-13-15(2)23-18-9-5-8-17(12-18)22-3/h4-10,12,15H,11,13H2,1-3H3,(H2,20,21)


Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: Ishigami T, Yoshioka K, Karicheti V, Marson L. A role for peripheral 5-HT2 receptors in serotonin-induced facilitation of the expulsion phase of ejaculation in male rats. J Sex Med. 2013 Nov;10(11):2688-702. doi: 10.1111/jsm.12306. Epub 2013 Sep 12. PubMed PMID: 24024794.

2: Lacolley P, Owen JR, Sandock K, Lewis TH, Bates JN, Robertson TP, Lewis SJ. 5-HT activates vagal afferent cell bodies in vivo: role of 5-HT2 and 5-HT3 receptors. Neuroscience. 2006 Nov 17;143(1):273-87. Epub 2006 Oct 9. PubMed PMID: 17029799.

3: Owen JR, Bates JN, Lewis SJ. Differential effects of nitroblue tetrazolium on the hemodynamic responses elicited by activation of alpha1-adrenoceptors and 5-HT2 receptors in conscious rats. Eur J Pharmacol. 2006 Mar 27;535(1-3):248-52. Epub 2006 Mar 9. PubMed PMID: 16527267.

4: Sipe K, Leventhal L, Burroughs K, Cosmi S, Johnston GH, Deecher DC. Serotonin 2A receptors modulate tail-skin temperature in two rodent models of estrogen deficiency-related thermoregulatory dysfunction. Brain Res. 2004 Dec 3;1028(2):191-202. PubMed PMID: 15527744.

5: Dave KD, Quinn JL, Harvey JA, Aloyo VJ. Role of central 5-HT2 receptors in mediating head bobs and body shakes in the rabbit. Pharmacol Biochem Behav. 2004 Mar;77(3):623-9. PubMed PMID: 15006475.

6: Johnson KW, Nelson DL, Dieckman DK, Wainscott DB, Lucaites VL, Audia JE, Owton WM, Phebus LA. Neurogenic dural protein extravasation induced by meta-chlorophenylpiperazine (mCPP) involves nitric oxide and 5-HT2B receptor activation. Cephalalgia. 2003 Mar;23(2):117-23. PubMed PMID: 12603368.

7: Yamada J, Sugimoto Y, Yoshikawa T, Horisaka K. Hyperglycemia induced by the 5-HT receptor agonist, 5-methoxytryptamine, in rats: involvement of the peripheral 5-HT2A receptor. Eur J Pharmacol. 1997 Apr 4;323(2-3):235-40. PubMed PMID: 9128844.

8: Danuser H, Thor KB. Spinal 5-HT2 receptor-mediated facilitation of pudendal nerve reflexes in the anaesthetized cat. Br J Pharmacol. 1996 May;118(1):150-4. PubMed PMID: 8733588; PubMed Central PMCID: PMC1909481.

9: Chaouche-Teyara K, Fournier B, Safar M, Dabiré H. Systemic and regional haemodynamic effects of 1-(2,5-dimethoxy-4-iodo-phenyl)-2-aminopropane (DOI) and alpha-methyl-5-HT, in the anaesthetised rat. Clin Exp Hypertens. 1994 Nov;16(6):779-98. PubMed PMID: 7858559.

10: Zabik JE, Sprague JE, Binkerd K. Central and peripheral components of the inhibitory actions of 5-HTP on ethanol consumption in the rat. Pharmacol Biochem Behav. 1994 Mar;47(3):547-51. PubMed PMID: 8208773.

11: Eberle-Wang K, Braun BT, Simansky KJ. Serotonin contracts the isolated rat pylorus via a 5-HT2-like receptor. Am J Physiol. 1994 Jan;266(1 Pt 2):R284-91. PubMed PMID: 8304552.

12: Lawton CL, Blundell JE. 5-HT and carbohydrate suppression: effects of 5-HT antagonists on the action of d-fenfluramine and DOI. Pharmacol Biochem Behav. 1993 Oct;46(2):349-60. PubMed PMID: 8265689.

13: Bailey SP, Davis JM, Ahlborn EN. Serotonergic agonists and antagonists affect endurance performance in the rat. Int J Sports Med. 1993 Aug;14(6):330-3. PubMed PMID: 8407063.

14: Chaouche-Teyara K, Dabiré H, Fournier B, Safar M. [Peripheral and central participation in hemodynamic effects of serotonin2 receptor stimulation]. Arch Mal Coeur Vaiss. 1993 Aug;86(8):1257-61. French. PubMed PMID: 8129539.

15: Grignaschi G, Mantelli B, Samanin R. The hypophagic effect of restraint stress in rats can be mediated by 5-HT2 receptors in the paraventricular nucleus of the hypothalamus. Neurosci Lett. 1993 Apr 2;152(1-2):103-6. PubMed PMID: 8515859.

16: Pérgola PE, Sved AF, Voogt JL, Alper RH. Effect of serotonin on vasopressin release: a comparison to corticosterone, prolactin and renin. Neuroendocrinology. 1993 Mar;57(3):550-8. PubMed PMID: 8321422.

17: Meller ST, Lewis SJ, Brody MJ, Gebhart GF. Vagal afferent-mediated inhibition of a nociceptive reflex by i.v. serotonin in the rat. II. Role of 5-HT receptor subtypes. Brain Res. 1992 Jul 10;585(1-2):71-86. PubMed PMID: 1511336.

18: Bond EF, Heitkemper MM, Gruver MK. Mediation of thyrotropin-releasing hormone induced gastric motility increases in developing rats. Eur J Pharmacol. 1992 Jul 7;217(2-3):127-35. PubMed PMID: 1425933.

19: Yamada J, Sugimoto Y, Kimura I, Watanabe Y, Takeuchi N, Horisaka K. Hyperglucagonemia induced in mice by tryptamine: involvement of the peripheral 5-HT2 receptors. Eur J Pharmacol. 1992 Jun 5;216(2):307-10. PubMed PMID: 1397014.

20: Grignaschi G, Samanin R. Role of serotonin and catecholamines in brain in the feeding suppressant effect of fluoxetine. Neuropharmacology. 1992 May;31(5):445-9. PubMed PMID: 1528396.