WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 341435

CAS#: 15301-97-0

Description: Xylocoumarol is a biochemical.

Chemical Structure

CAS# 15301-97-0

Theoretical Analysis

MedKoo Cat#: 341435
Name: Xylocoumarol
CAS#: 15301-97-0
Chemical Formula: C17H14O3
Exact Mass: 266.0943
Molecular Weight: 266.296
Elemental Analysis: C, 76.68; H, 5.30; O, 18.02

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: Xylocoumarol; BS 7173-D; Xilocumarol.

IUPAC/Chemical Name: 4-Hydroxy-3-(3,5-xylyl)coumarin


InChi Code: InChI=1S/C17H14O3/c1-10-7-11(2)9-12(8-10)15-16(18)13-5-3-4-6-14(13)20-17(15)19/h3-9,18H,1-2H3

SMILES Code: O=C1OC2=C(C=CC=C2)C(O)=C1C3=CC(C)=CC(C)=C3

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 266.296 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Rayar AM, Lagarde N, Martin F, Blanchard F, Liagre B, Ferroud C, Zagury JF, Montes M, Sylla-Iyarreta Veitía M. New selective cyclooxygenase-2 inhibitors from cyclocoumarol: Synthesis, characterization, biological evaluation and molecular modeling. Eur J Med Chem. 2018 Feb 25;146:577-587. doi: 10.1016/j.ejmech.2018.01.054. Epub 2018 Jan 31. PubMed PMID: 29407982.

2: He M, Korzekwa KR, Jones JP, Rettie AE, Trager WF. Structural forms of phenprocoumon and warfarin that are metabolized at the active site of CYP2C9. Arch Biochem Biophys. 1999 Dec 1;372(1):16-28. PubMed PMID: 10562412.

3: Maurer HH, Arlt JW. Detection of 4-hydroxycoumarin anticoagulants and their metabolites in urine as part of a systematic toxicological analysis procedure for acidic drugs and poisons by gas chromatography-mass spectrometry after extractive methylation. J Chromatogr B Biomed Sci Appl. 1998 Sep 4;714(2):181-95. PubMed PMID: 9766858.

4: Bourinbaiar AS, Tan X, Nagorny R. Inhibitory effect of coumarins on HIV-1 replication and cell-mediated or cell-free viral transmission. Acta Virol. 1993 Aug;37(4):241-50. PubMed PMID: 7905238.

5: Heimark LD, Trager WF. Stereoselective metabolism of conformational analogues of warfarin by beta-naphthoflavone-inducible cytochrome P-450. J Med Chem. 1985 Apr;28(4):503-6. PubMed PMID: 3981543.

6: Heimark LD, Trager WF. The preferred solution conformation of warfarin at the active site of cytochrome P-450 based on the CD spectra in octanol/water model system. J Med Chem. 1984 Aug;27(8):1092-5. PubMed PMID: 6747992.

7: BRUNTON L, LOWENSTEIN L, SHAPIRO L. Some experience with the anticoagulant cyclocumarol. Can Med Assoc J. 1955 Sep 1;73(5):392-5. PubMed PMID: 13250469; PubMed Central PMCID: PMC1826335.

8: MARION P, COLPRON G, LONG LA. [Study of cyclocumarol, its clinical aspects and its depressive action on prothrombin and on proconvertin]. Union Med Can. 1955 Apr;84(4):426-30. French. PubMed PMID: 14386612.

9: NEW and nonofficial remedies: cyclocumarol. J Am Med Assoc. 1952 Mar 15;148(11):939. PubMed PMID: 14897693.

10: SHAPIRO S. The hypoprothrombinemia-inducing activity of Link's compound 63 (methopyranorin). Acta Haematol. 1951 Sep;6(3):129-40. PubMed PMID: 14877466.