Xyloxemine (free base)

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MedKoo CAT#: 341431

CAS#: 1600-19-7 (free base)

Description: Xyloxemine (free base) is a biochemical.

Chemical Structure

Xyloxemine (free base)
CAS# 1600-19-7 (free base)

Theoretical Analysis

MedKoo Cat#: 341431
Name: Xyloxemine (free base)
CAS#: 1600-19-7 (free base)
Chemical Formula: C23H33NO2
Exact Mass: 355.25
Molecular Weight: 355.522
Elemental Analysis: C, 77.70; H, 9.36; N, 3.94; O, 9.00

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
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Related CAS #: 1600-19-7 (free base)   2827-06-7 (HCl)  

Synonym: Xyloxemine (free base); BS 6748; BS-6748; BS6748.

IUPAC/Chemical Name: 2-(2-(Di-2,6-xylylmethoxy)ethoxy)-N,N-dimethylethylamine


InChi Code: InChI=1S/C23H33NO2/c1-17-9-7-10-18(2)21(17)23(22-19(3)11-8-12-20(22)4)26-16-15-25-14-13-24(5)6/h7-12,23H,13-16H2,1-6H3

SMILES Code: Cc1cccc(c1C(c2c(cccc2C)C)OCCOCCN(C)C)C

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 355.52 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Hespe W, Prins H, Kafoe WF, Nauta WT. The distribution and metabolic fate of xyloxemine hydrochloride in mice and rats. Arch Int Pharmacodyn Ther. 1967 Dec;170(2):397-408. PubMed PMID: 6076587.

2: van Eeken CJ, Mulder D. The influence of xyloxemine hydrochloride, 2-[2-(DI-2,6-xylylmethoxy)ethoxy]-N,N-dimethylethylamine hydrochloride, on reproduction in laboratory animals. Arch Int Pharmacodyn Ther. 1967 May;167(1):135-41. PubMed PMID: 6035090.

3: Doorenbos HJ, Rekker RF, Nauta WT. Investigation of xyloxemine hydrochloride, 2-[2-(di-2,6-xylylmethoxy)ethoxy]-N,N-dimethylethylamine hydrochloride (BS 6748). Pharm Weekbl. 1966 Jul 1;101(26):565-9. PubMed PMID: 5916606.

4: Tersteege HM, Funcke AB, Louwerse WJ, Nauta WT. Pharmacological properties of xyloxemine hydrochloride, 2-[2-(di-2,6-xylylmethoxy) ethoxy]-N,N-dimethylethylamine hydrochloride (BS 6748), a new antitussive agent. Arch Int Pharmacodyn Ther. 1966 Jun;161(2):314-33. PubMed PMID: 5926874.