WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 341333
CAS#: 943832-60-8
Description: Halauxifen is a biochemical.
MedKoo Cat#: 341333
Name: Halauxifen
CAS#: 943832-60-8
Chemical Formula: C13H9Cl2FN2O3
Exact Mass: 329.9974
Molecular Weight: 331.1244
Elemental Analysis: C, 47.16; H, 2.74; Cl, 21.41; F, 5.74; N, 8.46; O, 14.50
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
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Synonym: Halauxifen; XDE-729; XDE 729; XDE729; XR-729; DE-729.
IUPAC/Chemical Name: 4-Amino-3-chloro-6-(4-chloro-2-fluoro-3-methoxyphenyl)-2-pyridinecarboxylic acid
InChi Key: KKLBEFSLWYDQFI-UHFFFAOYSA-N
InChi Code: InChI=1S/C13H9Cl2FN2O3/c1-21-12-6(14)3-2-5(10(12)16)8-4-7(17)9(15)11(18-8)13(19)20/h2-4H,1H3,(H2,17,18)(H,19,20)
SMILES Code: O=C(C1=NC(C2=CC=C(Cl)C(OC)=C2F)=CC(N)=C1Cl)O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 331.1244 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1: Kolanczyk RC, Serrano JA, Tapper MA, Schmieder PK. A comparison of fish pesticide metabolic pathways with those of the rat and goat. Regul Toxicol Pharmacol. 2018 Apr;94:124-143. doi: 10.1016/j.yrtph.2018.01.019. Epub 2018 Feb 6. PubMed PMID: 29407202.
2: Hoyerova K, Hosek P, Quareshy M, Li J, Klima P, Kubes M, Yemm AA, Neve P, Tripathi A, Bennett MJ, Napier RM. Auxin molecular field maps define AUX1 selectivity: many auxin herbicides are not substrates. New Phytol. 2018 Mar;217(4):1625-1639. doi: 10.1111/nph.14950. Epub 2017 Dec 19. PubMed PMID: 29265374.
3: Epp JB, Schmitzer PR, Crouse GD. Fifty years of herbicide research: comparing the discovery of trifluralin and halauxifen-methyl. Pest Manag Sci. 2018 Jan;74(1):9-16. doi: 10.1002/ps.4657. Epub 2017 Aug 24. PubMed PMID: 28675627.
4: Hannas BR, Ellis-Hutchings RG, Marshall VA, Terry C, McCoy AA, Saghir SA, Brooks K, Eisenbrandt D, Carney EW, Billington R, Rasoulpour RJ. Dietary Route of Exposure for Rabbit Developmental Toxicity Studies. Toxicol Sci. 2016 Nov;154(1):90-100. Epub 2016 Aug 4. PubMed PMID: 27492223.
5: Epp JB, Alexander AL, Balko TW, Buysse AM, Brewster WK, Bryan K, Daeuble JF, Fields SC, Gast RE, Green RA, Irvine NM, Lo WC, Lowe CT, Renga JM, Richburg JS, Ruiz JM, Satchivi NM, Schmitzer PR, Siddall TL, Webster JD, Weimer MR, Whiteker GT, Yerkes CN. The discovery of Arylex™ active and Rinskor™ active: Two novel auxin herbicides. Bioorg Med Chem. 2016 Feb 1;24(3):362-71. doi: 10.1016/j.bmc.2015.08.011. Epub 2015 Aug 19. PubMed PMID: 26321602.
6: Zhao H, Xu J, Dong F, Liu X, Wu Y, Wu X, Zheng Y. Simultaneous determination of three herbicides in wheat, wheat straw, and soil using a quick, easy, cheap, effective, rugged, and safe method with ultra high performance liquid chromatography and tandem mass spectrometry. J Sep Sci. 2015 Apr;38(7):1164-71. doi: 10.1002/jssc.201401234. Epub 2015 Feb 26. PubMed PMID: 25620026.
