WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 562550

CAS#: 927878-49-7

Description: TFC-007 is a hematopoietic prostaglandin D synthase (H-PGDS) inhibitor.

Chemical Structure

CAS# 927878-49-7

Theoretical Analysis

MedKoo Cat#: 562550
Name: TFC-007
CAS#: 927878-49-7
Chemical Formula: C27H29N5O4
Exact Mass: 487.222
Molecular Weight: 487.56
Elemental Analysis: C, 66.51; H, 6.00; N, 14.36; O, 13.13

Price and Availability

Size Price Availability Quantity
10.0mg USD 350.0 2 Weeks
50.0mg USD 1195.0 2 Weeks
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Synonym: TFC-007; TFC 007; TFC007;

IUPAC/Chemical Name: N-[4-[4-(4-Morpholinylcarbonyl)-1-piperidinyl]phenyl]-2-phenoxy-5-pyrimidinecarboxamide


InChi Code: InChI=1S/C27H29N5O4/c33-25(21-18-28-27(29-19-21)36-24-4-2-1-3-5-24)30-22-6-8-23(9-7-22)31-12-10-20(11-13-31)26(34)32-14-16-35-17-15-32/h1-9,18-20H,10-17H2,(H,30,33)


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 487.56 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Nabe T, Kuriyama Y, Mizutani N, Shibayama S, Hiromoto A, Fujii M, Tanaka K, Kohno S. Inhibition of hematopoietic prostaglandin D synthase improves allergic nasal blockage in guinea pigs. Prostaglandins Other Lipid Mediat. 2011 Aug;95(1-4):27-34. doi: 10.1016/j.prostaglandins.2011.05.001. Epub 2011 May 10. PubMed PMID: 21601002.


10.0mg / USD 350.0