B07 hydrochloride

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 562534

CAS#: 1260629-43-3 (free base)

Description: B07 hydrochloride is a CCR5 antagonist-based HIV-1 entry inhibitor.


Price and Availability

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B07 hydrochloride is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 562534
Name: B07 hydrochloride
CAS#: 1260629-43-3 (free base)
Chemical Formula: C29H40Cl3FN4O2
Exact Mass: 600.2201
Molecular Weight: 602.01
Elemental Analysis: C, 57.86; H, 6.70; Cl, 17.67; F, 3.16; N, 9.31; O, 5.32


Synonym: B07 hydrochloride; B-07 hydrochloride; B 07 hydrochloride; B07 HCl; B-07 HCl; B 07 HCl;

IUPAC/Chemical Name: 1-Acetyl-N-(3-chloro-4-methylphenyl)-N-[3-[4-[(4-fluorophenyl)methyl]-1-piperazinyl]propyl]-4-piperidinecarboxamide Dihydrochloride

InChi Key: DPGDWQZODLFWID-UHFFFAOYSA-N

InChi Code: InChI=1S/C29H38ClFN4O2.2ClH/c1-22-4-9-27(20-28(22)30)35(29(37)25-10-14-34(15-11-25)23(2)36)13-3-12-32-16-18-33(19-17-32)21-24-5-7-26(31)8-6-24;;/h4-9,20,25H,3,10-19,21H2,1-2H3;2*1H

SMILES Code: O=C(C1CCN(C(C)=O)CC1)N(C2=CC=C(C)C(Cl)=C2)CCCN3CCN(CC4=CC=C(F)C=C4)CC3.[H]Cl.[H]Cl


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1: Dong MX, Lu L, Li H, Wang X, Lu H, Jiang S, Dai QY. Design, synthesis, and biological activity of novel 1,4-disubstituted piperidine/piperazine derivatives as CCR5 antagonist-based HIV-1 entry inhibitors. Bioorg Med Chem Lett. 2012 May 1;22(9):3284-6. doi: 10.1016/j.bmcl.2012.03.019. Epub 2012 Mar 11. PubMed PMID: 22464131.