D44

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 562530

CAS#: 826998-10-1

Description: D44 is an inhibitor of Plasmodium FKBPs.


Price and Availability

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Price

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Price

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D44 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 562530
Name: D44
CAS#: 826998-10-1
Chemical Formula: C16H16N4OS
Exact Mass: 312.1045
Molecular Weight: 312.39
Elemental Analysis: C, 61.52; H, 5.16; N, 17.94; O, 5.12; S, 10.26


Synonym: D44; D-44; D 44;

IUPAC/Chemical Name: N-(2-Ethyl-phenyl)-2-(3H-imidazo[4,5-b]pyridin-2-ylsulfanyl)-acetamide

InChi Key: LGTSSAOGGPBTGN-UHFFFAOYSA-N

InChi Code: InChI=1S/C16H16N4OS/c1-2-11-6-3-4-7-12(11)18-14(21)10-22-16-19-13-8-5-9-17-15(13)20-16/h3-9H,2,10H2,1H3,(H,18,21)(H,17,19,20)

SMILES Code: O=C(NC1=CC=CC=C1CC)CSC2=NC3=CC=CN=C3N2


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1: Todescan S, Nizar R. Managing patients with necrotizing ulcerative periodontitis. J Can Dent Assoc. 2013;79:d44. Review. PubMed PMID: 23763731.

2: Titball RW. Clostridium perfringens vaccines. Vaccine. 2009 Nov 5;27 Suppl 4:D44-7. doi: 10.1016/j.vaccine.2009.07.047. Review. PubMed PMID: 19837285.

3: Bieniasz PD, Cullen BR. Chemokine receptors and human immunodeficiency virus infection. Front Biosci. 1998 Jan 1;3:d44-58. Review. PubMed PMID: 9407151.

4: Autran B, Plata F, Guillon JM, Joly P, Mayaud C, Debré P. HIV-specific cytotoxic T lymphocytes directed against alveolar macrophages in HIV-infected patients. Res Virol. 1990 Mar-Apr;141(2):131-6. Review. PubMed PMID: 2189171.