Bellidifolin

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MedKoo CAT#: 341309

CAS#: 2798-25-6

Description: Bellidifolin is a biochemical.


Price and Availability

Size Price Shipping out time Quantity
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Pricing updated 2020-08-10. Prices are subject to change without notice.

Bellidifolin is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 341309
Name: Bellidifolin
CAS#: 2798-25-6
Chemical Formula: C14H10O6
Exact Mass: 274.0477
Molecular Weight: 274.228
Elemental Analysis: C, 61.32; H, 3.68; O, 35.01


Synonym: Bellidifolin; BRN 0288441; CCRIS 5471; CCRIS-5471; CCRIS5471;

IUPAC/Chemical Name: Xanthen-9-one, 3-methoxy-1,5,8-trihydroxy-

InChi Key: JDIORNFCMMYMLF-UHFFFAOYSA-N

InChi Code: InChI=1S/C14H10O6/c1-19-6-4-9(17)11-10(5-6)20-14-8(16)3-2-7(15)12(14)13(11)18/h2-5,15-17H,1H3

SMILES Code: O=C1C2=C(OC3=C1C(O)=CC=C3O)C=C(OC)C=C2O


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001


References

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9: Singh PP, Ambika, Chauhan SM. Activity-guided isolation of antioxidant xanthones from Swertia chirayita (Roxb.) H. Karsten (Gentianaceae). Nat Prod Res. 2012;26(18):1682-6. doi: 10.1080/14786419.2011.592836. Epub 2011 Oct 10. PubMed PMID: 21985644.

10: Tian LY, Bai X, Chen XH, Fang JB, Liu SH, Chen JC. Anti-diabetic effect of methylswertianin and bellidifolin from Swertia punicea Hemsl. and its potential mechanism. Phytomedicine. 2010 Jun;17(7):533-9. doi: 10.1016/j.phymed.2009.10.007. Epub 2009 Dec 3. PubMed PMID: 19962285.

11: Xu K, Shen J, Li F, Liu J, Liu G, Tan J, Tan G. [Determination of six active components in three species of genus Swertia by HPLC multiwavelength with detection]. Zhongguo Zhong Yao Za Zhi. 2009 Jun;34(11):1384-9. Chinese. PubMed PMID: 19771868.

12: Janković T, Savikin K, Menković N, Aljancić I, Leskovac A, Petrović S, Joksić G. Radioprotective effects of Gentianella austriaca fractions and polyphenolic constituents in human lymphocytes. Planta Med. 2008 Jun;74(7):736-40. doi: 10.1055/s-2008-1074524. Epub 2008 Apr 29. PubMed PMID: 18446672.

13: Urbain A, Marston A, Grilo LS, Bravo J, Purev O, Purevsuren B, Batsuren D, Reist M, Carrupt PA, Hostettmann K. Xanthones from Gentianella amarella ssp. acuta with acetylcholinesterase and monoamine oxidase inhibitory activities. J Nat Prod. 2008 May;71(5):895-7. doi: 10.1021/np070690l. Epub 2008 Mar 13. PubMed PMID: 18336006.

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15: Hirakawa K, Yoshida M, Nagatsu A, Mizukami H, Rana V, Rawat MS, Oikawa S, Kawanishi S. Chemopreventive action of xanthone derivatives on photosensitized DNA damage. Photochem Photobiol. 2005 Mar-Apr;81(2):314-9. PubMed PMID: 15646999.

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17: Menković N, Savikin-Fodulović K, Bulatović V, Aljancić I, Juranić N, Macura S, Vajs V, Milosavljević S. Xanthones from Swertia punctata. Phytochemistry. 2002 Oct;61(4):415-20. PubMed PMID: 12377236.

18: Basnet P, Kadota S, Shimizu M, Takata Y, Kobayashi M, Namba T. Bellidifolin stimulates glucose uptake in rat 1 fibroblasts and ameliorates hyperglycemia in streptozotocin (STZ)-induced diabetic rats. Planta Med. 1995 Oct;61(5):402-5. PubMed PMID: 7480198.

19: Basnet P, Kadota S, Shimizu M, Namba T. Bellidifolin: a potent hypoglycemic agent in streptozotocin (STZ)-induced diabetic rats from Swertia japonica. Planta Med. 1994 Dec;60(6):507-11. PubMed PMID: 7809201.

20: Matsushima T, Araki A, Yagame O, Muramatsu M, Koyama K, Ohsawa K, Natori S, Tomimori H. Mutagenicities of xanthone derivatives in Salmonella typhimurium TA100, TA98, TA97, and TA2637. Mutat Res. 1985 Jun-Jul;150(1-2):141-6. PubMed PMID: 3889613.