Naphthylvinylpyridine

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 341270

CAS#: 16375-56-7

Description: Naphthylvinylpyridine is a biochemical.


Chemical Structure

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Naphthylvinylpyridine
CAS# 16375-56-7

Theoretical Analysis

MedKoo Cat#: 341270
Name: Naphthylvinylpyridine
CAS#: 16375-56-7
Chemical Formula: C17H13N
Exact Mass: 231.10
Molecular Weight: 231.298
Elemental Analysis: C, 88.28; H, 5.67; N, 6.06

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: Naphthylvinylpyridine; Yub 25; Yub-25; Yub25.

IUPAC/Chemical Name: Pyridine, 4-(2-(1-naphthalenyl)ethenyl)-

InChi Key: FLKDRTOVVLNOLV-CMDGGOBGSA-N

InChi Code: InChI=1S/C17H13N/c1-2-7-17-15(4-1)5-3-6-16(17)9-8-14-10-12-18-13-11-14/h1-13H/b9-8+

SMILES Code: C1(/C=C/C2=C3C=CC=CC3=CC=C2)=CC=NC=C1

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 231.30 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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7: Hamel E, Assumel Lurdin C, Fage D, Edvinsson L, MacKenzie ET. Small pial vessels, but not choroid plexus, exhibit specific biochemical correlates of functional cholinergic innervation. Brain Res. 1990 May 21;516(2):301-9. PubMed PMID: 2364295.

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9: Carroll PT, Ivy MT. Effect of 2-(4-phenylpiperidino)cyclohexanol (AH 5183) on the veratridine-induced increase in acetylcholine synthesis by rat hippocampal tissue. J Neurochem. 1988 Sep;51(3):808-19. PubMed PMID: 3411328.

10: Carmeliet P, Denef C. Immunocytochemical and pharmacological evidence for an intrinsic cholinomimetic system modulating prolactin and growth hormone release in rat pituitary. Endocrinology. 1988 Aug;123(2):1128-39. PubMed PMID: 3293981.

11: Arnerić SP, Honig MA, Milner TA, Greco S, Iadecola C, Reis DJ. Neuronal and endothelial sites of acetylcholine synthesis and release associated with microvessels in rat cerebral cortex: ultrastructural and neurochemical studies. Brain Res. 1988 Jun 28;454(1-2):11-30. PubMed PMID: 3408997.

12: Gray AP, Platz RD, Henderson TR, Chang TC, Takahashi K, Dretchen KL. Approaches to protection against nerve agent poisoning. (Naphthylvinyl)pyridine derivatives as potential antidotes. J Med Chem. 1988 Apr;31(4):807-14. PubMed PMID: 3351860.

13: Molinengo L, Orsetti M. Acetylcholine levels in the spinal cord after atropine, diisopropylfluorophosphate and naphthylvinylpyridine. Arch Int Pharmacodyn Ther. 1987 Sep;289(1):18-24. PubMed PMID: 3435202.

14: Carroll PT, Badamchian M, Craig P, Lyness WH. Veratridine-induced breakdown of cytosolic acetylcholine in rat hippocampal minces: an intraterminal form of acetylcholinesterase or choline O-acetyltransferase? Brain Res. 1986 Sep 24;383(1-2):83-99. PubMed PMID: 3768708.

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18: Chweh AY, DeBernardis JF, Siuda JF, Rondan NG, Abola JE, Abraham DJ. Structural correlations of choline acetyltransferase inhibitors: trans-N-(carboxymethyl)-4-(beta-1-naphthylvinyl)pyridinium bromide and cis-N-(2-aminoethyl)-4-(beta-1-naphthylvinyl)-3-methylpyridinium bromide hydrobromide. J Med Chem. 1984 Jul;27(7):825-30. PubMed PMID: 6737426.

19: Benishin CG, Carroll PT. Multiple forms of choline-O-acetyltransferase in mouse and rat brain: solubilization and characterization. J Neurochem. 1983 Oct;41(4):1030-9. PubMed PMID: 6619842.

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