B355252
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 341187

CAS#: 1261576-81-1

Description: B355252 is a neuroprotective agent that potentiates nerve growth factor (NGF)-induced neurite outgrowth and protects against cell death caused by glutamate-evoked oxidative stress.


Price and Availability

Size
Price

10mg
USD 205
Size
Price

50mg
USD 450
Size
Price

B355252 purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 341187
Name: B355252
CAS#: 1261576-81-1
Chemical Formula: C25H24ClN3O3S2
Exact Mass: 513.0948
Molecular Weight: 514.055
Elemental Analysis: C, 58.41; H, 4.71; Cl, 6.90; N, 8.17; O, 9.34; S, 12.47


Synonym: B355252; B 355252; B-355252.

IUPAC/Chemical Name: 4-Chloro-N-(naphthalen-1-ylmethyl)-5-(3-(piperazin-1-yl)phenoxy)thiophene-2-sulfonamide

InChi Key: YAAVQYDOVJQDFZ-UHFFFAOYSA-N

InChi Code: InChI=1S/C25H24ClN3O3S2/c26-23-16-24(34(30,31)28-17-19-7-3-6-18-5-1-2-10-22(18)19)33-25(23)32-21-9-4-8-20(15-21)29-13-11-27-12-14-29/h1-10,15-16,27-28H,11-14,17H2

SMILES Code: O=S(C1=CC(Cl)=C(OC2=CC=CC(N3CCNCC3)=C2)S1)(NCC4=C5C=CC=CC5=CC=C4)=O


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1: Gliyazova NS, Ibeanu GC. The Chemical Molecule B355252 is Neuroprotective in
an In Vitro Model of Parkinson's Disease. Cell Mol Neurobiol. 2016
Oct;36(7):1109-22. doi: 10.1007/s10571-015-0304-5. Epub 2015 Dec 9. PubMed PMID: 26649727.

2: Gliyazova NS, Huh EY, Ibeanu GC. A novel phenoxy thiophene sulphonamide
molecule protects against glutamate evoked oxidative injury in a neuronal cell
model. BMC Neurosci. 2013 Sep 2;14:93. doi: 10.1186/1471-2202-14-93. PubMed PMID:
24004478; PubMed Central PMCID: PMC3846642.