Bamb-4

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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 562354

CAS#: 891025-25-5

Description: Bamb-4 is a highly membrane-permeable inhibitor of inositol-1,4,5-trisphosphate-3-kinase A (ITPKA). It acts by suppressing the metastasis-promoting effect of ITPKA in lung tumor cells.


Price and Availability

Size Price Shipping out time Quantity
Inquire bulk and customized quantity

Pricing updated 2020-10-26. Prices are subject to change without notice.

Bamb-4 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 562354
Name: Bamb-4
CAS#: 891025-25-5
Chemical Formula: C15H12N2O2
Exact Mass: 252.0899
Molecular Weight: 252.27
Elemental Analysis: C, 71.42; H, 4.79; N, 11.10; O, 12.68


Synonym: Bamb-4; Bamb 4; Bamb4;

IUPAC/Chemical Name: N-(1,2-benzoxazol-3-yl)-4-methylbenzamide

InChi Key: IEPCQLHHUYRTEY-UHFFFAOYSA-N

InChi Code: InChI=1S/C15H12N2O2/c1-10-6-8-11(9-7-10)15(18)16-14-12-4-2-3-5-13(12)19-17-14/h2-9H,1H3,(H,16,17,18)

SMILES Code: O=C(NC1=NOC2=CC=CC=C12)C3=CC=C(C)C=C3


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001


References

1: Schröder D, Tödter K, Gonzalez B, Franco-Echevarría E, Rohaly G, Blecher C, Lin HY, Mayr GW, Windhorst S. The new InsP3Kinase inhibitor BIP-4 is competitive to InsP3 and blocks proliferation and adhesion of lung cancer cells. Biochem Pharmacol. 2015 Jul 15;96(2):143-50. doi: 10.1016/j.bcp.2015.05.004. Epub 2015 May 15. PubMed PMID: 25986882.

2: Schröder D, Rehbach C, Seyffarth C, Neuenschwander M, Kries JV, Windhorst S. Identification of a new membrane-permeable inhibitor against inositol-1,4,5-trisphosphate-3-kinase A. Biochem Biophys Res Commun. 2013 Sep 20;439(2):228-34. doi: 10.1016/j.bbrc.2013.08.053. Epub 2013 Aug 24. PubMed PMID: 23981806.