Racemic Tamsulosin

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 341160

CAS#: 94666-07-6

Description: Racemic Tamsulosin is a biochemical.

Chemical Structure

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Racemic Tamsulosin
CAS# 94666-07-6
Instruction

Theoretical Analysis

MedKoo Cat#: 341160
Name: Racemic Tamsulosin
CAS#: 94666-07-6
Chemical Formula: C20H28N2O5S
Exact Mass: 408.17
Molecular Weight: 408.513
Elemental Analysis: C, 58.80; H, 6.91; N, 6.86; O, 19.58; S, 7.85

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: Racemic Tamsulosin; YM-12617; YM 12617; YM12617.

IUPAC/Chemical Name: Benzenesulfonamide, 5-(2-((2-(2-ethoxyphenoxy)ethyl)amino)propyl)-2-methoxy-

InChi Key: DRHKJLXJIQTDTD-UHFFFAOYSA-N

InChi Code: InChI=1S/C20H28N2O5S/c1-4-26-17-7-5-6-8-18(17)27-12-11-22-15(2)13-16-9-10-19(25-3)20(14-16)28(21,23)24/h5-10,14-15,22H,4,11-13H2,1-3H3,(H2,21,23,24)

SMILES Code: CCOc1ccccc1OCCNC(C)Cc2ccc(c(c2)S(=O)(=O)N)OC

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 408.51 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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3: Novotna A, Kamenickova A, Pecova M, Korhonova M, Bartonkova I, Dvorak Z. Profiling of enantiopure drugs towards aryl hydrocarbon (AhR), glucocorticoid (GR) and pregnane X (PXR) receptors in human reporter cell lines. Chem Biol Interact. 2014 Feb 5;208:64-76. doi: 10.1016/j.cbi.2013.11.018. Epub 2013 Dec 6. PubMed PMID: 24316275.

4: Kasawar GB, Farooqui MN. Stability Indicating HPLC Method for the Determination of Chiral Purity of R-(-)-5-[2-aminopropyl]-2-methoxybenzene Sulfonamide. Indian J Pharm Sci. 2009 Sep;71(5):533-7. doi: 10.4103/0250-474X.58187. PubMed PMID: 20502572; PubMed Central PMCID: PMC2866345.

5: Gizur T, Fogassy E, Bálint J, Egri G, Törley J, Demeter A, Greiner I. New practical synthesis of Tamsulosin. Chirality. 2008 Jun;20(6):790-5. doi: 10.1002/chir.20544. PubMed PMID: 18306291.

6: Kavalírová A, Pospísilová M, Karlícek R. Enantiomeric purity determination of tamsulosin by capillary electrophoresis using cyclodextrins and a polyacrylamide-coated capillary. Farmaco. 2005 Oct;60(10):834-9. Epub 2005 Aug 31. PubMed PMID: 16139279.

7: Rolan P, Terpstra IJ, Clarke C, Mullins F, Visser JN. A placebo-controlled pharmacodynamic and pharmacokinetic interaction study between tamsulosin and acenocoumarol. Br J Clin Pharmacol. 2003 Mar;55(3):314-6. PubMed PMID: 12630984; PubMed Central PMCID: PMC1884205.