WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 581133
Description: DA 4360 is H2-receptor antagonism. The compounds which were investigated in a wider concentration range, i.e. DA 4360, DA 4577, and DA 4626, behaved as simple competitive antagonists, yielding apparent KB values comparable with those estimated in conventional H2-receptor assays. These results provide further evidence for the highly selective H2-receptor antagonism of these new molecules, and confirm the suitability of the histamine-stimulated adenylate cyclase assay in guinea-pig gastric cells as a functionally reduced system for the study of H2 antagonists.
MedKoo Cat#: 581133
Name: DA 4360
Chemical Formula: C11H12N4
Exact Mass: 200.1062
Molecular Weight: 200.24
Elemental Analysis: C, 65.98; H, 6.04; N, 27.98
Synonym: DA 4360; DA-4360; DA4360;
IUPAC/Chemical Name: (Z)-N-(4-(1H-imidazol-4-yl)phenyl)-N'-methylformimidamide
InChi Key: ATPATFRGZLKLMA-UHFFFAOYSA-N
InChi Code: 1S/C11H12N4/c1-12-7-14-10-4-2-9(3-5-10)11-6-13-8-15-11/h2-8H,1H3,(H,12,14)(H,13,15)
SMILES Code: C(=N\C)\Nc1ccc(cc1)c1nc[nH]c1
1: Spahn H, Mutschler E. [Determination of feprazone and one of its metabolites in human plasma after high-performance liquid chromatographic or thin-layer chromatographic separation]. J Chromatogr. 1982 Oct 8;232(1):145-53. German. PubMed PMID: 7142323.