DA 4360

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 581133

CAS#: 83184-12-7

Description: DA 4360 is H2-receptor antagonism. The compounds which were investigated in a wider concentration range, i.e. DA 4360, DA 4577, and DA 4626, behaved as simple competitive antagonists, yielding apparent KB values comparable with those estimated in conventional H2-receptor assays. These results provide further evidence for the highly selective H2-receptor antagonism of these new molecules, and confirm the suitability of the histamine-stimulated adenylate cyclase assay in guinea-pig gastric cells as a functionally reduced system for the study of H2 antagonists.


Price and Availability

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DA 4360 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 581133
Name: DA 4360
CAS#: 83184-12-7
Chemical Formula: C11H12N4
Exact Mass: 200.1062
Molecular Weight: 200.24
Elemental Analysis: C, 65.98; H, 6.04; N, 27.98


Synonym: DA 4360; DA-4360; DA4360;

IUPAC/Chemical Name: (Z)-N-(4-(1H-imidazol-4-yl)phenyl)-N'-methylformimidamide

InChi Key: ATPATFRGZLKLMA-UHFFFAOYSA-N

InChi Code: 1S/C11H12N4/c1-12-7-14-10-4-2-9(3-5-10)11-6-13-8-15-11/h2-8H,1H3,(H,12,14)(H,13,15)

SMILES Code: C(=N\C)\Nc1ccc(cc1)c1nc[nH]c1


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1: Spahn H, Mutschler E. [Determination of feprazone and one of its metabolites in human plasma after high-performance liquid chromatographic or thin-layer chromatographic separation]. J Chromatogr. 1982 Oct 8;232(1):145-53. German. PubMed PMID: 7142323.