D 2343

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MedKoo CAT#: 584369

CAS#: 72734-63-5

Description: D 2343 is a Beta 2-adrenoreceptor agonist with alpha 1-adrenoreceptor blocking properties. This compound has 5-6 times lower potency than terbutaline, but has a longer bronchodilating effect.

Price and Availability

Size Price Shipping out time Quantity
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Pricing updated 2020-06-03. Prices are subject to change without notice.

D 2343 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 584369
Name: D 2343
CAS#: 72734-63-5
Chemical Formula: C20H27NO3
Exact Mass: 329.1991
Molecular Weight: 329.44
Elemental Analysis: C, 72.92; H, 8.26; N, 4.25; O, 14.57

Synonym: D 2343; D2343; D-2343

IUPAC/Chemical Name: Benzenemethanol, 4-hydroxy-alpha-(((3-(2-methoxyphenyl)-1,1-dimethylpropyl)amino)methyl)-


InChi Code: InChI=1S/C20H27NO3/c1-20(2,13-12-16-6-4-5-7-19(16)24-3)21-14-18(23)15-8-10-17(22)11-9-15/h4-11,18,21-23H,12-14H2,1-3H3


Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: Löfdahl CG, Bengtsson B, Svedmyr K, Svedmyr N. Two new beta 2-adrenoceptor agonists, D-2343 and QH 25, studied in asthmatic patients. Allergy. 1982 Jul;37(5):351-7. PubMed PMID: 6127039.

2: Löfdahl CG, Svedmyr N. Selectivity of beta-adrenergic stimulating and blocking agents. Eur J Respir Dis Suppl. 1984;136:101-13. PubMed PMID: 6145618.

3: Löfdahl CG, Svedmyr K, Svedmyr N, Andersson P, Bengtsson B, Olsson OA, Waldeck B. Comparison of beta 2-adrenoceptor stimulation in bronchial and skeletal muscle in experimental and clinical studies. Eur J Respir Dis Suppl. 1984;135:124-7. PubMed PMID: 6329798.

4: Olsson OA, Gustafsson B. The effect of D2343 in transmurally stimulated rabbit isthmus muscle. Acta Pharmacol Toxicol (Copenh). 1985 May;56(5):427-30. PubMed PMID: 2863921.

5: Löfdahl CG, Svedmyr N. A new beta 2-adrenoceptor agonist--D 2343--with long duration. Inhalation comparison with terbutaline in asthmatics. Allergy. 1984 Aug;39(6):485-9. PubMed PMID: 6437263.

6: Olsson OA, Ahlquist B, Gustafsson B. A new beta 2-adrenoceptor agonist with alpha 1-adrenoceptor blocking properties. Acta Pharmacol Toxicol (Copenh). 1981 Apr;48(4):340-8. PubMed PMID: 6121453.

7: Ingemarsson I, Arulkumaran S, Chua S. Effects of D2343, a new beta-mimetic drug, and terbutaline on spontaneous term labor. Gynecol Obstet Invest. 1988;26(2):130-5. PubMed PMID: 3146531.

8: Olsson OA, Ahlquist B, Gustafsson B, Persson G. The effects in myometrial preparations of D2343, a beta 2-adrenoceptor agonist possessing alpha 1-receptor blocking qualities. Acta Pharmacol Toxicol (Copenh). 1984 Nov;55(5):391-7. PubMed PMID: 6152105.