BVT-116429

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MedKoo CAT#: 562275

CAS#: 870710-02-4

Description: BVT-116429 is a 11β-HSD1 inhibitor.


Price and Availability

Size Price Shipping out time Quantity
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Pricing updated 2020-08-15. Prices are subject to change without notice.

BVT-116429 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 562275
Name: BVT-116429
CAS#: 870710-02-4
Chemical Formula: C13H12F4N2OS
Exact Mass: 320.0606
Molecular Weight: 320.3
Elemental Analysis: C, 48.75; H, 3.78; F, 23.73; N, 8.75; O, 4.99; S, 10.01


Synonym: BVT-116429; BVT 116429; BVT116429;

IUPAC/Chemical Name: (5S)-2-[[(1S)-1-(2-Fluorophenyl)ethyl]amino]-5-methyl-5-(trifluoromethyl)-4(5H)-thiazolone

InChi Key: KNHNFKZUNFPPQE-MADCSZMMSA-N

InChi Code: InChI=1S/C13H12F4N2OS/c1-7(8-5-3-4-6-9(8)14)18-11-19-10(20)12(2,21-11)13(15,16)17/h3-7H,1-2H3,(H,18,19,20)/t7-,12-/m0/s1

SMILES Code: O=C1N=C(N[C@H](C2=CC=CC=C2F)C)S[C@]1(C)C(F)(F)F


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001


References

1: Sundbom M, Kaiser C, Björkstrand E, Castro VM, Larsson C, Selén G, Nyhem CS, James SR. Inhibition of 11betaHSD1 with the S-phenylethylaminothiazolone BVT116429 increases adiponectin concentrations and improves glucose homeostasis in diabetic KKAy mice. BMC Pharmacol. 2008 Feb 12;8:3. doi: 10.1186/1471-2210-8-3. PubMed PMID: 18269730; PubMed Central PMCID: PMC2270815.