D 15413

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 584367

CAS#: 83364-03-8

Description: D 15413 has an inhibitory effect on estrogen-dependent mammary tumors.


Price and Availability

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Price

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D 15413 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 584367
Name: D 15413
CAS#: 83364-03-8
Chemical Formula: C16H12Cl3NO2
Exact Mass: 354.9934
Molecular Weight: 356.627
Elemental Analysis: C, 53.89; H, 3.39; Cl, 29.82; N, 3.93; O, 8.97


Synonym: D 15413; D15413; D-15413

IUPAC/Chemical Name: Indol-6-ol, 4-chloro-2-(2,6-dichloro-4-hydroxyphenyl)-1-ethyl-

InChi Key: ZATDYQOGSPTLBG-UHFFFAOYSA-N

InChi Code: InChI=1S/C16H12Cl3NO2/c1-2-20-14-6-9(22)3-11(17)10(14)7-15(20)16-12(18)4-8(21)5-13(16)19/h3-7,21-22H,2H2,1H3

SMILES Code: OC1=CC2=C(C(Cl)=C1)C=C(C3=C(Cl)C=C(O)C=C3Cl)N2CC


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1: von Angerer E, Prekajac J, Schneider MR, Berger MR. The inhibitory effect of 4-chloro-2-(2,6-dichloro-4-hydroxyphenyl)-1-ethyl-6-hydroxyindole (D 15413) on estrogen-dependent mammary tumors. J Cancer Res Clin Oncol. 1985;110(3):216-20. PubMed PMID: 4077919.

2: Schneider MR, von Angerer E, Höhn W, Sinowatz F. Antitumor activity of antiestrogenic phenylindoles on experimental prostate tumors. Eur J Cancer Clin Oncol. 1987 Jul;23(7):1005-15. PubMed PMID: 3665986.

3: von Angerer E, Prekajac J. 2-(Hydroxyphenyl)indoles: a new class of mammary tumor inhibiting compounds. J Med Chem. 1983 Jan;26(1):113-6. PubMed PMID: 6402593.