WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 584367
Description: D 15413 has an inhibitory effect on estrogen-dependent mammary tumors.
MedKoo Cat#: 584367
Name: D 15413
Chemical Formula: C16H12Cl3NO2
Exact Mass: 354.9934
Molecular Weight: 356.627
Elemental Analysis: C, 53.89; H, 3.39; Cl, 29.82; N, 3.93; O, 8.97
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.
Synonym: D 15413; D15413; D-15413
IUPAC/Chemical Name: Indol-6-ol, 4-chloro-2-(2,6-dichloro-4-hydroxyphenyl)-1-ethyl-
InChi Key: ZATDYQOGSPTLBG-UHFFFAOYSA-N
InChi Code: InChI=1S/C16H12Cl3NO2/c1-2-20-14-6-9(22)3-11(17)10(14)7-15(20)16-12(18)4-8(21)5-13(16)19/h3-7,21-22H,2H2,1H3
SMILES Code: OC1=CC2=C(C(Cl)=C1)C=C(C3=C(Cl)C=C(O)C=C3Cl)N2CC
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 356.627 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: von Angerer E, Prekajac J, Schneider MR, Berger MR. The inhibitory effect of 4-chloro-2-(2,6-dichloro-4-hydroxyphenyl)-1-ethyl-6-hydroxyindole (D 15413) on estrogen-dependent mammary tumors. J Cancer Res Clin Oncol. 1985;110(3):216-20. PubMed PMID: 4077919.
2: Schneider MR, von Angerer E, Höhn W, Sinowatz F. Antitumor activity of antiestrogenic phenylindoles on experimental prostate tumors. Eur J Cancer Clin Oncol. 1987 Jul;23(7):1005-15. PubMed PMID: 3665986.
3: von Angerer E, Prekajac J. 2-(Hydroxyphenyl)indoles: a new class of mammary tumor inhibiting compounds. J Med Chem. 1983 Jan;26(1):113-6. PubMed PMID: 6402593.