BYK191023 Dihydrochloride

We are open as normal during COVID-19 pandemic. Order online, same day shipping out from North Carolina, USA

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 562265

CAS#: 1216722-25-6

Description: BYK191023 Dihydrochloride is a selective inhibitor of inducible nitric oxide synthase (iNOS), acting in an NADPH- and time-dependent manner.

Price and Availability

Size Price Shipping out time Quantity
5mg USD 230 2 Weeks
10mg USD 400 2 Weeks
50mg USD 1010 2 Weeks
Inquire bulk and customized quantity

Pricing updated 2020-08-15. Prices are subject to change without notice.

BYK191023 Dihydrochloride, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 562265
Name: BYK191023 Dihydrochloride
CAS#: 1216722-25-6
Chemical Formula: C14H16Cl2N4O
Exact Mass: 326.0701
Molecular Weight: 327.2
Elemental Analysis: C, 51.39; H, 4.93; Cl, 21.67; N, 17.12; O, 4.89

Synonym: BYK191023 Dihydrochloride; BYK-191023 Dihydrochloride; BYK 191023 Dihydrochloride; BYK191023 2HCl; BYK-191023 2HCl; BYK 191023 2HCl;

IUPAC/Chemical Name: 2-[2-(4-Methoxy-2-pyridinyl)ethyl]-1H-imidazo[4,5-b]pyridine dihydrochloride


InChi Code: InChI=1S/C14H14N4O.2ClH/c1-19-11-6-8-15-10(9-11)4-5-13-17-12-3-2-7-16-14(12)18-13;;/h2-3,6-9H,4-5H2,1H3,(H,16,17,18);2*1H


Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: Stahl W, Matejovic M, Radermacher P. Inhibition of nitric oxide synthase during sepsis: revival because of isoform selectivity? Shock. 2010 Sep;34(3):321-2. doi: 10.1097/SHK.0b013e3181d758b5. PubMed PMID: 20601934.

2: Su F, Huang H, Akieda K, Occhipinti G, Donadello K, Piagnerelli M, De Backer D, Vincent JL. Effects of a selective iNOS inhibitor versus norepinephrine in the treatment of septic shock. Shock. 2010 Sep;34(3):243-9. doi: 10.1097/SHK.0b013e3181d75967. PubMed PMID: 20160666.

3: Tiso M, Strub A, Hesslinger C, Kenney CT, Boer R, Stuehr DJ. BYK191023 (2-[2-(4-methoxy-pyridin-2-yl)-ethyl]-3h-imidazo[4,5-b]pyridine) is an NADPH- and time-dependent irreversible inhibitor of inducible nitric-oxide synthase. Mol Pharmacol. 2008 Apr;73(4):1244-53. doi: 10.1124/mol.107.041319. Epub 2008 Jan 4. PubMed PMID: 18178668.

4: Lehner MD, Marx D, Boer R, Strub A, Hesslinger C, Eltze M, Ulrich WR, Schwoebel F, Schermuly RT, Barsig J. In vivo characterization of the novel imidazopyridine BYK191023 [2-[2-(4-methoxy-pyridin-2-yl)-ethyl]-3H-imidazo[4,5-b]pyridine], a potent and highly selective inhibitor of inducible nitric-oxide synthase. J Pharmacol Exp Ther. 2006 Apr;317(1):181-7. Epub 2005 Dec 20. PubMed PMID: 16368897.

5: Strub A, Ulrich WR, Hesslinger C, Eltze M, Fuchss T, Strassner J, Strand S, Lehner MD, Boer R. The novel imidazopyridine 2-[2-(4-methoxy-pyridin-2-yl)-ethyl]-3H-imidazo[4,5-b]pyridine (BYK191023) is a highly selective inhibitor of the inducible nitric-oxide synthase. Mol Pharmacol. 2006 Jan;69(1):328-37. Epub 2005 Oct 13. PubMed PMID: 16223957.