WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 341087
Description: Y 25510 is a biochemical.
MedKoo Cat#: 341087
Name: Y 25510
Chemical Formula: C19H22N4O3
Exact Mass: 354.1692
Molecular Weight: 354.41
Elemental Analysis: C, 64.39; H, 6.26; N, 15.81; O, 13.54
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.
Synonym: Y 25510; Y-25510; Y25510.
IUPAC/Chemical Name: 1H-Pyrazolo(3,4-b)pyridine-1-acetic acid, 3-(4-(2-(dimethylamino)-1-methylethoxy)phenyl)-, (+-)-
InChi Key: DYLPVOLNSXUKPG-UHFFFAOYSA-N
InChi Code: InChI=1S/C19H22N4O3/c1-13(11-22(2)3)26-15-8-6-14(7-9-15)18-16-5-4-10-20-19(16)23(21-18)12-17(24)25/h4-10,13H,11-12H2,1-3H3,(H,24,25)
SMILES Code: CC(CN(C)C)Oc1ccc(cc1)c2c3cccnc3n(n2)CC(=O)O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 354.41 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Azuma J, Ogura M, Yamamoto I, Hisadome M, Fukuda T, Ikeda Y, Mori H, Oka T, Asano S. The effect of Y-25510 injection on the serum levels of some cytokines in healthy adult volunteers. Eur J Clin Pharmacol. 1998 Feb;53(6):411-9. PubMed PMID: 9551699.
2: Kusuhara H, Komatsu H, Hisadome M, Ikeda Y. (+/-)-3-[4-(2-dimethylamino-1-methylethoxy)-phenyl]-1H-pyrazolo[3,4- B]pyridine-1-acetic acid (Y-25510) stimulates production of IL-1 beta and IL-6 at the level of messenger RNA expression in cultured human monocytes. Int J Immunopharmacol. 1996 Dec;18(12):719-28. PubMed PMID: 9172015.
3: Hisadome M, Fukuda T, Matsuyuki H, Ikeda Y, Nomoto K. Enhancement of in vivo production of IL-1 alpha and IL-6 in mice by Y-25510, a 1H-pyrazolo[3,4-b]pyridine-1 acetic acid derivative. Int J Immunopharmacol. 1996 Jun-Jul;18(6-7):379-84. PubMed PMID: 9024939.
4: Hisadome M, Fukuda T, Terasawa M, Oe T, Takahata H, Goto K, Tsuru S, Nomoto K. Enhancement of host defense by Y-25510, (+-)-3-[4-(2-dimethylamino-1-methylethoxy)phenyl]-1H-pyrazolo[3,4 -b] pyridine-1-acetic acid, a novel synthetic compound. A comparison with recombinant human granulocyte colony-stimulating factor in 5-fluorouracil-treated mice. Int J Immunopharmacol. 1992 Oct;14(7):1195-201. PubMed PMID: 1280628.