Y 26611

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 341088

CAS#: 143375-60-4

Description: Y 26611 is a biochemical.


Chemical Structure

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Y 26611
CAS# 143375-60-4

Theoretical Analysis

MedKoo Cat#: 341088
Name: Y 26611
CAS#: 143375-60-4
Chemical Formula: C18H19F2N3O4
Exact Mass: 379.1344
Molecular Weight: 379.3638
Elemental Analysis: C, 56.99; H, 5.05; F, 10.02; N, 11.08; O, 16.87

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: Y 26611; Y-26611; Y26611.

IUPAC/Chemical Name: Y 26611

InChi Key: MVKGRIHKSLEKTE-UHFFFAOYSA-N

InChi Code: InChI=1S/C18H19F2N3O4/c19-13-5-11-15(14(20)16(13)22-3-4-27-10(6-21)7-22)23(9-1-2-9)8-12(17(11)24)18(25)26/h5,8-10H,1-4,6-7,21H2,(H,25,26)

SMILES Code: c1c2c(c(c(c1F)N3CCOC(C3)CN)F)n(cc(c2=O)C(=O)O)C4CC4

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 379.3638 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Sakurai N, Sano M, Hirayama F, Kuroda T, Uemori S, Moriguchi A, Yamamoto K, Ikeda Y, Kawakita T. Synthesis and structure-activity relationships of 7-(2-aminoalkyl)morpholinoquinolones as anti-Helicobacter pylori agents. Bioorg Med Chem Lett. 1998 Aug 18;8(16):2185-90. Erratum in: Bioorg Med Chem Lett 1998 Oct 20;8(20):2937. PubMed PMID: 9873510.

2: Akter U, Niwa M, Nose T, Kaida T, Matsuno H, Kozawa O, Uematsu T. Effects of several agents on UVB- and UVA plus systemic fluoroquinolone-induced erythema of guinea pig skin evaluated by reflectance colorimetry. Free Radic Biol Med. 1998 May;24(7-8):1113-9. PubMed PMID: 9626565.

3: Wada K, Saniabadi AR, Umemura K, Nakano M, Ito T, Nakashima M. Direct measurement of superoxide-dependent chemiluminescence from rat skin following UV-dependent fluoroquinolone-induced dermatitis. Free Radic Biol Med. 1995 May;18(5):923-7. PubMed PMID: 7797102.

4: Kubo S, Matsumoto T, Takahashi K, Haraoka M, Tanaka M, Sakumoto M, Sakamoto Y, Kumazawa J. Enhanced chemiluminescence response of polymorphonuclear leukocytes by new quinolone antimicrobials. Chemotherapy. 1994 Sep-Oct;40(5):333-6. PubMed PMID: 7956457.

5: Wada K, Saniabadi AR, Umemura K, Takiguchi Y, Nakashima M. UV-dependent quinolone-induced human erythrocyte membrane lipid peroxidation: studies on the phototoxicity of Y-26611, a new quinolone derivative. Pharmacol Toxicol. 1994 Apr-May;74(4-5):240-3. PubMed PMID: 8090693.

6: Araki K, Kuroda T, Uemori S, Moriguchi A, Ikeda Y, Hirayama F, Yokoyama Y, Iwao E, Yakushiji T. Quinolone antimicrobial agents substituted with morpholines at the 7-position. Syntheses and structure-activity relationships. J Med Chem. 1993 May 14;36(10):1356-63. PubMed PMID: 8388467.

7: Tomioka H, Sato K, Saito H. [Antimicrobial activity of new quinolones against Mycobacterium avium and Mycobacterium intracellulare determined by the dilution methods using 7H11 agar and Ogawa egg media]. Kekkaku. 1993 May;68(5):367-70. Japanese. PubMed PMID: 8331881.

8: Tomioka H, Sato K, Saito H, Ikeda Y. [Antimycobacterial activity of a newly synthesized fluoroquinolone, Y-26611]. Kekkaku. 1992 Jul;67(7):515-20. Japanese. PubMed PMID: 1331603.