D 595

We are open as normal during COVID-19 pandemic. Order online, same day shipping out.

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 581087

CAS#: 16740-29-7

Description: D595 (10(-5) M), is a phenethylamine-type calcium channel blocker. The most potent phenylalkylamine with respect to negative inotropy was (+/-)-D 595 with an EC50-value of 794 nmol/l.

Price and Availability

Size Price Shipping out time Quantity
Inquire bulk and customized quantity

Pricing updated 2020-06-06. Prices are subject to change without notice.

D 595 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 581087
Name: D 595
CAS#: 16740-29-7
Chemical Formula: C25H32Cl2N2O2
Exact Mass: 462.1841
Molecular Weight: 463.44
Elemental Analysis: C, 64.79; H, 6.96; Cl, 15.30; N, 6.04; O, 6.90

Synonym: D 595; D-595; D595;

IUPAC/Chemical Name: Benzeneacetonitrile, 3,4-dichloro-alpha-(3-((2-(3,4-dimethoxyphenyl)ethyl)methylamino)propyl)-alpha-(1-methylethyl)-


InChi Code: InChI=1S/C25H32Cl2N2O2/c1-18(2)25(17-28,20-8-9-21(26)22(27)16-20)12-6-13-29(3)14-11-19-7-10-23(30-4)24(15-19)31-5/h7-10,15-16,18H,6,11-14H2,1-5H3


Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


5: Clark JM, Brooks MW. Role of ion channels and intraterminal calcium homeostasis in the action of deltamethrin at presynaptic nerve terminals. Biochem Pharmacol. 1989 Jul 15;38(14):2233-45. PubMed PMID: 2546560.

6: Goll A, Glossmann H, Mannhold R. Correlation between the negative inotropic potency and binding parameters of 1,4-dihydropyridine and phenylalkylamine calcium channel blockers in cat heart. Naunyn Schmiedebergs Arch Pharmacol. 1986 Nov;334(3):303-12. PubMed PMID: 3027587.