D4-Ribavirin

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 581084

CAS#: 131922-28-6

Description: D4-Ribavirin is isolated from the brine shrimp active fraction of the MeOH extract of the starfish Certonardoa semiregularis. The structures were determined on the basis of spectral analysis and chemical manipulation. The compounds were evaluated for antiviral activity against HIV, HSV, CoxB, EMCV, and VSV and displayed insignificant activity within the range of noncytotoxic concentrations.


Price and Availability

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D4-Ribavirin is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 581084
Name: D4-Ribavirin
CAS#: 131922-28-6
Chemical Formula: C8H10N4O3
Exact Mass: 210.0753
Molecular Weight: 210.19
Elemental Analysis: C, 45.71; H, 4.80; N, 26.66; O, 22.83


Synonym: D4-Ribavirin; D4 Ribavirin; D4Ribavirin;

IUPAC/Chemical Name: 1H-1,2,4-Triazole-3-carboxamide, 1-(2,5-dihydro-5-(hydroxymethyl)-2-furanyl)-, (2R-cis)-

InChi Key: RAQSTELPKQLBOP-NTSWFWBYSA-N

InChi Code: InChI=1S/C8H10N4O3/c9-7(14)8-10-4-12(11-8)6-2-1-5(3-13)15-6/h1-2,4-6,13H,3H2,(H2,9,14)/t5-,6+/m0/s1

SMILES Code: O=C(C1=NN([C@@H]2O[C@H](CO)C=C2)C=N1)N


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1: Wang W, Li F, Alam N, Liu Y, Hong J, Lee CK, Im KS, Jung JH. New saponins from
the starfish Certonardoa semiregularis. J Nat Prod. 2002 Nov;65(11):1649-56.
PubMed PMID: 12444692.