WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 581083
Description: D4DAP is HIV virus replication inhibitor.
MedKoo Cat#: 581083
Chemical Formula: C10H12N6O2
Exact Mass: 248.1022
Molecular Weight: 248.25
Elemental Analysis: C, 48.38; H, 4.87; N, 33.85; O, 12.89
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.
Synonym: D4DAP; Ddedapr;
IUPAC/Chemical Name: Adenosine, 2-amino-2',3'-didehydro-2',3'-dideoxy-
InChi Key: QVRGWJZTKCMSIW-NTSWFWBYSA-N
InChi Code: QVRGWJZTKCMSIW-NTSWFWBYSA-N
SMILES Code: OC[C@@H]1C=C[C@H](N2C=NC3=C(N=C(N)N=C32)N)O1
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 248.25 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Balzarini J, Robins MJ, Zou RM, Herdewijn P, De Clercq E. The 2',3'-dideoxyriboside of 2,6-diaminopurine and its 2',3'-didehydro derivative inhibit the deamination of 2',3'-dideoxyadenosine, an inhibitor of human immunodeficiency virus (HIV) replication. Biochem Biophys Res Commun. 1987 May 29;145(1):277-83. PubMed PMID: 3496090.
2: Balzarini J, De Clercq E. The antiviral activity of 9-beta-D-arabinofuranosyladenine is enhanced by the 2',3'-dideoxyriboside, the 2',3'-didehydro-2',3'-dideoxyriboside and the 3'-azido-2',3'-dideoxyriboside of 2,6-diaminopurine. Biochem Biophys Res Commun. 1989 Feb 28;159(1):61-7. PubMed PMID: 2538128.
3: Balzarini J, Pauwels R, Baba M, Robins MJ, Zou RM, Herdewijn P, De Clercq E. The 2',3'-dideoxyriboside of 2,6-diaminopurine selectively inhibits human immunodeficiency virus (HIV) replication in vitro. Biochem Biophys Res Commun. 1987 May 29;145(1):269-76. PubMed PMID: 3496089.