Beaucage reagent
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 562119

CAS#: 66304-01-6

Description: Beaucage reagent is a DNA cleavage reagent.


Price and Availability

Size
Price

1g
USD 205
Size
Price

5g
USD 500
Size
Price

Beaucage reagent, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 562119
Name: Beaucage reagent
CAS#: 66304-01-6
Chemical Formula: C7H4O3S2
Exact Mass: 199.9602
Molecular Weight: 200.22
Elemental Analysis: C, 41.99; H, 2.01; O, 23.97; S, 32.02


Synonym: Beaucage reagent;

IUPAC/Chemical Name: 3H-Benzo[c][1,2]dithiol-3-one 1,1-dioxide

InChi Key: JUDOLRSMWHVKGX-UHFFFAOYSA-N

InChi Code: InChI=1S/C7H4O3S2/c8-7-5-3-1-2-4-6(5)12(9,10)11-7/h1-4H

SMILES Code: O=C1C2=CC=CC=C2S(S1)(=O)=O


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1: Manoharan M, Lu Y, Casper MD, Just G. Allyl group as a protecting group for internucleotide phosphate and thiophosphate linkages in oligonucleotide synthesis: facile oxidation and deprotection conditions. Org Lett. 2000 Feb 10;2(3):243-6. PubMed PMID: 10814292.

2: Xu Q, Musier-Forsyth K, Hammer RP, Barany G. Use of 1,2,4-dithiazolidine-3,5-dione (DtsNH) and 3-ethoxy-1,2,4-dithiazoline-5-one (EDITH) for synthesis of phosphorothioate-containing oligodeoxyribonucleotides. Nucleic Acids Res. 1996 May 1;24(9):1602-7. PubMed PMID: 8649975; PubMed Central PMCID: PMC145860.

3: Lesiak K, Khamnei S, Torrence PF. 2',5'-Oligoadenylate:antisense chimeras--synthesis and properties. Bioconjug Chem. 1993 Nov-Dec;4(6):467-72. PubMed PMID: 8305516.