BD1063 HCl

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MedKoo CAT#: 555158

CAS#: 206996-13-6 (HCl)

Description: BD1063 is a selective sigma receptor antagonist, with a reported binding affinity of Ki = 9 ± 1 nM for the sigma-1 receptor and more than 49 times selectivity over the sigma-2 receptor. Consistent with other reported sigma receptor antagonists, pretreating Swiss Webster mice with BD1063 significantly decreases the convulsivity and lethality of cocaine. In other animal studies, BD1063 blocks the effects of MDMA, and reduces alcohol intake in rodent models of alcoholism.

Price and Availability

Size Price Shipping out time Quantity
100mg USD 1250 2 Weeks
200mg USD 1950 2 Weeks
500mg USD 2950 2 Weeks
1g USD 3850 2 Weeks
2g USD 6450 2 Weeks
Inquire bulk and customized quantity

Pricing updated 2020-10-19. Prices are subject to change without notice.

BD1063 HCl, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 555158
Name: BD1063 HCl
CAS#: 206996-13-6 (HCl)
Chemical Formula: C13H20Cl4N2
Exact Mass:
Molecular Weight: 346.117
Elemental Analysis: C, 45.11; H, 5.82; Cl, 40.97; N, 8.09

Synonym: 206996-13-6 (HCl), 150208-28-9 (free base),

IUPAC/Chemical Name: 1-[2-(3,4-dichlorophenyl)ethyl]-4-methyl-piperazine, dihydrochloride


InChi Code: InChI=1S/C13H18Cl2N2.2ClH/c1-16-6-8-17(9-7-16)5-4-11-2-3-12(14)13(15)10-11;;/h2-3,10H,4-9H2,1H3;2*1H

SMILES Code: CN1CCN(CCC2=CC=C(Cl)C(Cl)=C2)CC1.[H]Cl.[H]Cl

Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


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8: Pan B, Guo Y, Kwok WM, Hogan Q, Wu HE. Sigma-1 receptor antagonism restores injury-induced decrease of voltage-gated Ca2+ current in sensory neurons. J Pharmacol Exp Ther. 2014 Aug;350(2):290-300. doi: 10.1124/jpet.114.214320. Epub 2014 Jun 2. PubMed PMID: 24891452; PubMed Central PMCID: PMC4109486.

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18: Liu Y, Matsumoto RR. Alterations in fos-related antigen 2 and sigma1 receptor gene and protein expression are associated with the development of cocaine-induced behavioral sensitization: time course and regional distribution studies. J Pharmacol Exp Ther. 2008 Oct;327(1):187-95. doi: 10.1124/jpet.108.141051. Epub 2008 Jun 30. PubMed PMID: 18591217.

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