WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 562022
CAS#: 957-68-6
Description: 7-ACS, also known as 7-Aminocephalosporinic acid, is a potent inhibitor of bacterial (S. aureus) β-lactamase.
MedKoo Cat#: 562022
Name: 7-ACS
CAS#: 957-68-6
Chemical Formula: C10H12N2O5S
Exact Mass: 272.0467
Molecular Weight: 272.27
Elemental Analysis: C, 44.11; H, 4.44; N, 10.29; O, 29.38; S, 11.77
Synonym: 7-ACS; 7 ACS; 7ACS; 7-Aminocephalosporinic acid; 7 Aminocephalosporinic acid; 7Aminocephalosporinic acid;
IUPAC/Chemical Name: (6R,7R)-3-(Acetyloxymethyl)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
InChi Key: HSHGZXNAXBPPDL-HZGVNTEJSA-N
InChi Code: InChI=1S/C10H12N2O5S/c1-4(13)17-2-5-3-18-9-6(11)8(14)12(9)7(5)10(15)16/h6,9H,2-3,11H2,1H3,(H,15,16)/t6-,9-/m1/s1
SMILES Code: O=C(C(N12)=C(COC(C)=O)CS[C@]2([H])[C@H](N)C1=O)O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 272.27 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1: Endoh T, Yagihashi A, Sasaki M, Watanabe N. Ceftizoxime-induced hemolysis due to immune complexes: case report and determination of the epitope responsible for immune complex-mediated hemolysis. Transfusion. 1999 Mar;39(3):306-9. PubMed PMID: 10204595.
