WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 527692
CAS#: 20535-76-6
Description: p18SMI-21 is a novel INK4C inhibitor, specifically blocking the bioactivity of p18 protein.
MedKoo Cat#: 527692
Name: p18SMI-21
CAS#: 20535-76-6
Chemical Formula: C10H14N2O4S
Exact Mass: 258.0674
Molecular Weight: 258.292
Elemental Analysis: C, 46.50; H, 5.46; N, 10.85; O, 24.78; S, 12.41
This product is not in stock, which may be available by custom synthesis.
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Synonym: p18SMI21; p18SMI 21; p18SMI-21
IUPAC/Chemical Name: N-[4-(2-Hydroxyethylsulfamoyl)phenyl]acetamide
InChi Key: VUYBWFBHHFQGDM-UHFFFAOYSA-N
InChi Code: InChI=1S/C10H14N2O4S/c1-8(14)12-9-2-4-10(5-3-9)17(15,16)11-6-7-13/h2-5,11,13H,6-7H2,1H3,(H,12,14)
SMILES Code: CC(NC1=CC=C(S(=O)(NCCO)=O)C=C1)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 258.292 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1: Isaac O, Thiemer K. [Biochemical studies on camomile components/III. In vitro studies about the antipeptic activity of (--)-alpha-bisabolol (author's transl)]. Arzneimittelforschung. 1975 Sep;25(9):1352-4. German. PubMed PMID: 21.
