p18SMI-41

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 527691

CAS#: 1111287-26-3

Description: p18SMI-41 is a novel INK4C inhibitor, specifically blocking the bioactivity of p18 protein.


Price and Availability

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p18SMI-41 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 527691
Name: p18SMI-41
CAS#: 1111287-26-3
Chemical Formula: C19H16N2O4
Exact Mass: 336.111
Molecular Weight: 336.347
Elemental Analysis: C, 67.85; H, 4.80; N, 8.33; O, 19.03


Synonym: p18SMI41; p18SMI 41; p18SMI-41

IUPAC/Chemical Name: 4-Acetylamino-N-(4-methyl-2-oxo-2H-chromen-7-yl)-benzamide

InChi Key: FVHODORGQJKWTM-UHFFFAOYSA-N

InChi Code: InChI=1S/C19H16N2O4/c1-11-9-18(23)25-17-10-15(7-8-16(11)17)21-19(24)13-3-5-14(6-4-13)20-12(2)22/h3-10H,1-2H3,(H,20,22)(H,21,24)

SMILES Code: O=C(NC1=CC(O2)=C(C=C1)C(C)=CC2=O)C3=CC=C(NC(C)=O)C=C3


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1: Stellwagen E, Babul J. Stabilization of the globular structure of ferricytochrome c by chloride in acidic solvents. Biochemistry. 1975 Nov 18;14(23):5135-40. PubMed PMID: 41.