Bts 39542

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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 584287

CAS#: 57410-31-8

Description: Bts 39542 is a diuretic. The ratio of the excretion of the major cations (sodium plus potassium) to that of the major anion (chloride) after BTS 39542 varied with species. In dogs, Bts 39542 exerts its major effects in the loop of Henle and increases renal blood flow but does not affect glomerular filtration rate.

Price and Availability

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Pricing updated 2020-03-30. Prices are subject to change without notice.

Bts 39542 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to to inquire quote.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 584287
Name: Bts 39542
CAS#: 57410-31-8
Chemical Formula: C16H11ClN4O3S
Exact Mass: 374.024
Molecular Weight: 374.799
Elemental Analysis: C, 51.27; H, 2.96; Cl, 9.46; N, 14.95; O, 12.81; S, 8.55

Synonym: Bts 39542; Bts39542; Bts-39542

IUPAC/Chemical Name: 1-Phthalazineacetic acid, 2-(1,2,3-benzothiadiazol-5-yl)-7-chloro-1,2,3,4-tetrahydro-4-oxo-


InChi Code: InChI=1S/C16H11ClN4O3S/c17-8-1-3-10-11(5-8)13(7-15(22)23)21(19-16(10)24)9-2-4-14-12(6-9)18-20-25-14/h1-6,13H,7H2,(H,19,24)(H,22,23)

SMILES Code: O=C(O)CC1N(C2=CC=C(SN=N3)C3=C2)NC(C4=C1C=C(Cl)C=C4)=O

Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: Cooling MJ, Sim MF. BTS 39542, a dihydrophthalazin-1-ylacetic acid with high efficacy diuretic activity. Br J Pharmacol. 1981 Oct;74(2):359-64. PubMed PMID: 7317685; PubMed Central PMCID: PMC2071724.

2: Aiton JF, Simmons NL. Diuretic action of BTS 39542 (dihydrophthalazin-1-ylacetic acid) is consistent with inhibition of Na + K + Cl cotransport. Biochem Pharmacol. 1982 Sep 1;31(17):2827-30. PubMed PMID: 7138578.