p18SMI-22

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 527690

CAS#: 1043924-66-8

Description: p18SMI-22 is a novel INK4C inhibitor, specifically blocking the bioactivity of p18 protein.


Price and Availability

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p18SMI-22 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 527690
Name: p18SMI-22
CAS#: 1043924-66-8
Chemical Formula: C17H18N2O5S
Exact Mass: 362.0936
Molecular Weight: 362.4
Elemental Analysis: C, 56.34; H, 5.01; N, 7.73; O, 22.07; S, 8.85


Synonym: p18SMI22; p18SMI 22; p18SMI-22

IUPAC/Chemical Name: Methyl (R)-(4-Acetylamino-benzenesulfonylamino)-phenyl-acetate

InChi Key: YUIQPNUBSVAFPL-MRXNPFEDSA-N

InChi Code: InChI=1S/C17H18N2O5S/c1-12(20)18-14-8-10-15(11-9-14)25(22,23)19-16(17(21)24-2)13-6-4-3-5-7-13/h3-11,16,19H,1-2H3,(H,18,20)/t16-/m1/s1

SMILES Code: O=C(OC)[C@H](NS(=O)(C1=CC=C(NC(C)=O)C=C1)=O)C2=CC=CC=C2


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1: Ardenne M, Reitnauer PG. [Demonstration of tumor inhibiting properties of a strongly immunostimulating low-molecular weight substance. Comparative studies with ifosfamide on the immuno-labile DS carcinosarcoma. Stimulation of the autoimmune activity for approx. 20 days by BA 1, a N-(2-cyanoethylene)-urea. Novel prophylactic possibilities]. Arzneimittelforschung. 1975 Sep;25(9):1369-79. German. PubMed PMID: 22.