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MedKoo CAT#: 561840

CAS#: 1446113-23-0

Description: Belvarafenib, also known as GDC-5573, HM95573, RG6185, is a selective inhibitor of the RAF family kinases designed to inhibit the MAPK pathway, which is frequently activated in human tumors and drives tumor growth.

Price and Availability

Size Price Shipping out time Quantity
5mg USD 90 Same day
10mg USD 150 Same day
25mg USD 250 Same day
50mg USD 450 Same day
100mg USD 850 Same day
200mg USD 1350 Same day
500mg USD 2450 Same day
1g USD 3450 Same day
2g USD 6250 Same day
Inquire bulk and customized quantity

Pricing updated 2020-10-29. Prices are subject to change without notice.

Belvarafenib, purity > 98%, is out of stock. The same day shipping after order is received.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 561840
Name: Belvarafenib
CAS#: 1446113-23-0
Chemical Formula: C23H18ClFN6OS
Exact Mass: 480.0935
Molecular Weight: 480.94
Elemental Analysis: C, 57.44; H, 3.77; Cl, 7.37; F, 3.95; N, 17.47; O, 3.33; S, 6.67

Synonym: Belvarafenib; GDC-5573; GDC5573; GDC 5573; HM95573; HM 95573; HM-95573; RG6185; RG-6185; RG 6185;

IUPAC/Chemical Name: 4-amino-N-(1-((3-chloro-2-fluorophenyl)amino)-6-methyl-4a,8a-dihydroisoquinolin-5-yl)thieno[3,2-d]pyrimidine-7-carboxamide


InChi Code: InChI=1S/C23H18ClFN6OS/c1-11-5-6-13-12(7-8-27-22(13)30-16-4-2-3-15(24)17(16)25)18(11)31-23(32)14-9-33-20-19(14)28-10-29-21(20)26/h2-10,12-13H,1H3,(H,27,30)(H,31,32)(H2,26,28,29)


Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Certificate of Analysis:

Safety Data Sheet (SDS):

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: