Belvarafenib
featured

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 561840

CAS#: 1446113-23-0

Description: Belvarafenib, also known as GDC-5573, HM95573, RG6185, is a selective inhibitor of the RAF family kinases designed to inhibit the MAPK pathway, which is frequently activated in human tumors and drives tumor growth.


Price and Availability

Size
Price

10mg
USD 200
100mg
USD 1250
1g
USD 3450
Size
Price

25mg
USD 450
200mg
USD 1850
2g
USD 5859
Size
Price

50mg
USD 750
500mg
USD 2450

Belvarafenib, purity > 98%, is out of stock. The same day shipping after order is received.


Chemical Structure

img

Theoretical Analysis

MedKoo Cat#: 561840
Name: Belvarafenib
CAS#: 1446113-23-0
Chemical Formula: C23H18ClFN6OS
Exact Mass: 480.0935
Molecular Weight: 480.94
Elemental Analysis: C, 57.44; H, 3.77; Cl, 7.37; F, 3.95; N, 17.47; O, 3.33; S, 6.67


Synonym: Belvarafenib; GDC-5573; GDC5573; GDC 5573; HM95573; HM 95573; HM-95573; RG6185; RG-6185; RG 6185;

IUPAC/Chemical Name: 4-amino-N-(1-((3-chloro-2-fluorophenyl)amino)-6-methyl-4a,8a-dihydroisoquinolin-5-yl)thieno[3,2-d]pyrimidine-7-carboxamide

InChi Key: SYPNJOBBCOQFCM-UHFFFAOYSA-N

InChi Code: InChI=1S/C23H18ClFN6OS/c1-11-5-6-13-12(7-8-27-22(13)30-16-4-2-3-15(24)17(16)25)18(11)31-23(32)14-9-33-20-19(14)28-10-29-21(20)26/h2-10,12-13H,1H3,(H,27,30)(H,31,32)(H2,26,28,29)

SMILES Code: O=C(C1=CSC2=C(N)N=CN=C21)NC3=C(C)C=CC4C(NC5=CC=CC(Cl)=C5F)=NC=CC34


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Certificate of Analysis:

Safety Data Sheet (MSDS):

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
2934.99.90.01