Bromocriptine Mesylate | CAS#22260-51-1 | dopamine agonist

Bromocriptine Mesylate
featured

WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 561823

CAS#: 22260-51-1

Description: Bromocriptine Mesylate is a dopamine agonist for the treatment of pituitary tumors, Parkinson's disease (PD), hyperprolactinaemia, neuroleptic malignant syndrome, and type 2 diabetes.

Chemical Structure

Bromocriptine Mesylate

CAS# 22260-51-1

Instruction

Theoretical Analysis

MedKoo Cat#: 561823
Name: Bromocriptine Mesylate
CAS#: 22260-51-1
Chemical Formula: C33H44BrN5O8S
Exact Mass: 0.00
Molecular Weight: 750.700
Elemental Analysis: C, 52.80; H, 5.91; Br, 10.64; N, 9.33; O, 17.05; S, 4.27

Price and Availability

Size	Price	Availability	Quantity
50mg	USD 190
100mg	USD 320
250mg	USD 590
Bulk inquiry Welcome, Customer: Please do not inquire quote if your intended use is for a patient since our products are for research use and for chemical synthesis use, not for human use . For in-stock products, we listed price in the web page. You may inquire prices for which sizes were not listed. If no price is listed, this means the product is not in stock at the moment, which may be available via custom synthesis. For cost-effective reason, minimum order of 1g is requested (typically very expensive). The lead time is usually 2-4 months. Quote of less than 1g will not be provided. MedKoo may not offer quote for below reasons: (1) current available synthetic method appears to be extremely expensive which is obviously not affordable to most customers; (2) Key raw material to make the product is temporally not available; (3) DEA controlled substances; (4) the product is under patent protection in customer’s country.

Synonym: Bromocriptine Mesylate; 2-Bromoergocryptine Mesylate;

IUPAC/Chemical Name: (6aR,9R)-5-Bromo-N-((2R,5S,10aS,10bS)-10b-hydroxy-5-isobutyl-2-isopropyl-3,6-dioxooctahydro-8H-oxazolo[3,2-a]pyrrolo[2,1-c]pyrazin-2-yl)-7-methyl-4,6,6a,7,8,9-hexahydroindolo[4,3-fg]quinoline-9-carboxamide methanesulfonate

InChi Key: NOJMTMIRQRDZMT-GSPXQYRGSA-N

InChi Code: InChI=1S/C32H40BrN5O5.CH4O3S/c1-16(2)12-24-29(40)37-11-7-10-25(37)32(42)38(24)30(41)31(43-32,17(3)4)35-28(39)18-13-20-19-8-6-9-22-26(19)21(27(33)34-22)14-23(20)36(5)15-18;1-5(2,3)4/h6,8-9,13,16-18,23-25,34,42H,7,10-12,14-15H2,1-5H3,(H,35,39);1H3,(H,2,3,4)/t18-,23-,24+,25+,31-,32+;/m1./s1

SMILES Code: O=C([C@H](C=C12)CN(C)[C@]2([H])CC3=C(Br)NC4=C3C1=CC=C4)N[C@@](O5)(C(C)C)C(N6[C@]5(O)[C@@](CCC7)([H])N7C([C@@H]6CC(C)C)=O)=O.CS(=O)(O)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Instruction:

View handling instruction

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 750.70 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

Formulation protocol:
In vitro protocol:
In vivo protocol:

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

Mass

Concentration

Volume

M. Wt* g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Concentration 1

Volume 1

Concentration 2

Volume 2

1: Brietzke SA. Oral antihyperglycemic treatment options for type 2 diabetes mellitus. Med Clin North Am. 2015 Jan;99(1):87-106. doi: 10.1016/j.mcna.2014.08.012. Epub 2014 Oct 18. Review. PubMed PMID: 25456645.

2: Weiland CM, Hilaire ML. Bromocriptine mesylate (Cycloset) for type 2 diabetes mellitus. Am Fam Physician. 2013 May 15;87(10):718-20. Review. PubMed PMID: 23939451.

3: Kerr JL, Timpe EM, Petkewicz KA. Bromocriptine mesylate for glycemic management in type 2 diabetes mellitus. Ann Pharmacother. 2010 Nov;44(11):1777-85. doi: 10.1345/aph.1P271. Epub 2010 Oct 26. Review. PubMed PMID: 20978217.

4: O'Keeffe ST. Restless legs syndrome. A review. Arch Intern Med. 1996 Feb 12;156(3):243-8. Review. PubMed PMID: 8572833.

5: Guay AT. Erectile dysfunction. Are you prepared to discuss it? Postgrad Med. 1995 Apr;97(4):127-30, 133-5, 139-40 passim. Review. PubMed PMID: 7716086.

6: Iffy L. Lethal cardiovascular complications in patients receiving bromocriptine for ablactation. Med Law. 1995;14(1-2):99-104. Review. PubMed PMID: 7666753.

7: Ahlskog JE. Treatment of Parkinson's disease. From theory to practice. Postgrad Med. 1994 Apr;95(5):52-4, 57-8, 61-4 passim. Review. PubMed PMID: 8153048.

8: Rampertaap MP. Neuroleptic malignant syndrome. South Med J. 1986 Mar;79(3):331-6. Review. PubMed PMID: 3513330.

Your view history

Bromocriptine Mesylate featured