WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 527081

CAS#: 452-06-2

Description: 2-Aminopurine is a specific inhibitor of double-stranded RNA-dependent protein kinase, protein kinase R (PKR).

Chemical Structure

CAS# 452-06-2

Theoretical Analysis

MedKoo Cat#: 527081
Name: 2-Aminopurine
CAS#: 452-06-2
Chemical Formula: C5H5N5
Exact Mass: 135.0545
Molecular Weight: 135.13
Elemental Analysis: C, 44.44; H, 3.73; N, 51.83

Price and Availability

Size Price Availability Quantity
100.0mg USD 270.0 2 Weeks
250.0mg USD 450.0 2 Weeks
500.0mg USD 820.0 2 Weeks
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Synonym: 2-Aminopurine

IUPAC/Chemical Name: 7H-Purin-2-ylamine


InChi Code: InChI=1S/C5H5N5/c6-5-7-1-3-4(10-5)9-2-8-3/h1-2H,(H3,6,7,8,9,10)


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 135.13 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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14: Buchanan HS, Pauff SM, Kosmidis TD, Taladriz-Sender A, Rutherford OI, Hatit MZC, Fenner S, Watson AJB, Burley GA. Correction to "Modular, Step-Efficient Palladium-Catalyzed Cross-Coupling Strategy To Access C6-Heteroaryl 2-Aminopurine Ribonucleosides". Org Lett. 2017 Aug 18;19(16):4411. doi: 10.1021/acs.orglett.7b02273. Epub 2017 Aug 2. PubMed PMID: 28766342.

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20: Saran R, Yao L, Hoang P, Liu J. Folding of the silver aptamer in a DNAzyme probed by 2-aminopurine fluorescence. Biochimie. 2017 Jul 12. pii: S0300-9084(17)30172-4. doi: 10.1016/j.biochi.2017.07.001. [Epub ahead of print] PubMed PMID: 28711684.