Z-DEVD-fmk
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 561669

CAS#: 210344-95-9

Description: Z-DEVD-fmk is a cell-permeable, irreversible inhibitor of caspase-3. Caspase-3 is a cysteinyl aspartate-specific protease which plays a central role in apoptosis.


Chemical Structure

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Z-DEVD-fmk
CAS# 210344-95-9

Theoretical Analysis

MedKoo Cat#: 561669
Name: Z-DEVD-fmk
CAS#: 210344-95-9
Chemical Formula: C30H41FN4O12
Exact Mass: 668.2705
Molecular Weight: 668.67
Elemental Analysis: C, 53.89; H, 6.18; F, 2.84; N, 8.38; O, 28.71

Price and Availability

Size Price Availability Quantity
25.0mg USD 950.0 2 Weeks
50.0mg USD 1650.0 2 Weeks
100.0mg USD 2650.0 2 Weeks
200.0mg USD 4650.0 2 Weeks
500.0mg USD 6650.0 2 Weeks
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Synonym: Z-DEVD-fmk; Z DEVD fmk; ZDEVDfmk;

IUPAC/Chemical Name: methyl (5S,8S,11S,14S)-14-(2-fluoroacetyl)-11-isopropyl-5-(2-methoxy-2-oxoethyl)-8-(3-methoxy-3-oxopropyl)-3,6,9,12-tetraoxo-1-phenyl-2-oxa-4,7,10,13-tetraazahexadecan-16-oate

InChi Key: GBJVAVGBSGRRKN-JYEBCORGSA-N

InChi Code: InChI=1S/C30H41FN4O12/c1-17(2)26(29(42)33-20(22(36)15-31)13-24(38)45-4)35-27(40)19(11-12-23(37)44-3)32-28(41)21(14-25(39)46-5)34-30(43)47-16-18-9-7-6-8-10-18/h6-10,17,19-21,26H,11-16H2,1-5H3,(H,32,41)(H,33,42)(H,34,43)(H,35,40)/t19-,20-,21-,26-/m0/s1

SMILES Code: O=C(OC)CC[C@H](NC([C@@H](NC(OCC1=CC=CC=C1)=O)CC(OC)=O)=O)C(N[C@@H](C(C)C)C(N[C@H](C(CF)=O)CC(OC)=O)=O)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 668.67 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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