B 746

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 584113

CAS#: 103051-26-9

Description: B 746 is an antibacterial agent primarily used in therapy for leprosy and Mycobacterium avium infections as well as against Mycobacterium tuberculosis, including those with multi-drug resistance.

Chemical Structure

B 746
CAS# 103051-26-9

Theoretical Analysis

MedKoo Cat#: 584113
Name: B 746
CAS#: 103051-26-9
Chemical Formula: C26H20Cl2N4
Exact Mass: 458.1065
Molecular Weight: 459.37
Elemental Analysis: C, 67.98; H, 4.39; Cl, 15.43; N, 12.20

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: B 746; B-746; B746

IUPAC/Chemical Name: Phenazine, 3-p-chloroanilino-10-(p-chlorophenyl)-2-(ethylimino)-2,10-dihydro-


InChi Code: InChI=1S/C26H20Cl2N4/c1-2-29-22-16-26-24(15-23(22)30-19-11-7-17(27)8-12-19)31-21-5-3-4-6-25(21)32(26)20-13-9-18(28)10-14-20/h3-16,30H,2H2,1H3/b29-22+

SMILES Code: CC/N=C1C=C2N(C3=CC=C(Cl)C=C3)C4=C(C=CC=C4)N=C2C=C\1NC5=CC=C(Cl)C=C5

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 459.37 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Jagannath C, Reddy MV, Kailasam S, O'Sullivan JF, Gangadharam PR. Chemotherapeutic activity of clofazimine and its analogues against Mycobacterium tuberculosis. In vitro, intracellular, and in vivo studies. Am J Respir Crit Care Med. 1995 Apr;151(4):1083-6. PubMed PMID: 7697235.

2: Gangadharam PR, Ashtekar D, O'Sullivan JF. In vitro, in vivo, and intracellular chemotherapeutic activity of B746, a clofazimine analogue against Mycobacterium avium complex. Tuber Lung Dis. 1992 Aug;73(4):192-9. PubMed PMID: 1477384.