B1912

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 584103

CAS#: 24028-59-9

Description: B1912 is an antibacterial agent.


Chemical Structure

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B1912
CAS# 24028-59-9

Theoretical Analysis

MedKoo Cat#: 584103
Name: B1912
CAS#: 24028-59-9
Chemical Formula: C30H29ClN4
Exact Mass: 480.2081
Molecular Weight: 481.04
Elemental Analysis: C, 74.91; H, 6.08; Cl, 7.37; N, 11.65

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: B1912; B-1912; B 1912.

IUPAC/Chemical Name: 8-Chloro-3-(cyclohexylmino)-3,5-dihydro-N,5-diphenyl-2-phenazinamine

InChi Key: HTAJQJZZHQMHBK-UHFFFAOYSA-N

InChi Code: InChI=1S/C30H29ClN4/c31-21-16-17-29-27(18-21)34-28-19-25(32-22-10-4-1-5-11-22)26(33-23-12-6-2-7-13-23)20-30(28)35(29)24-14-8-3-9-15-24/h1,3-5,8-11,14-20,23,26,32-33H,2,6-7,12-13H2

SMILES Code: ClC1=CC2=C(C=C1)N(C3=CC=CC=C3)C4=CC(NC5CCCCC5)C(NC6=CC=CC=C6)=CC4=N2

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 481.04 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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Reconstitution Calculator

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1: Moynihan R. Canadian media company demands right to publish direct to consumer drug advertising. BMJ. 2009 May 8;338:b1912. doi: 10.1136/bmj.b1912. PubMed PMID: 19429658.

2: Morrison NE. Abortifacient activity of B1912. Int J Lepr Other Mycobact Dis. 1979 Dec;47(4):613-4. PubMed PMID: 122637.

3: Reich CV, de la Cruz E. The effect on pregnant mice of 0.05% B1912 fed in the diet. Int J Lepr Other Mycobact Dis. 1979 Dec;47(4):612-3. PubMed PMID: 122636.

4: Morrison NE, Marley GM. Comparative DNA binding studies with clofazimine and B1912. Int J Lepr Other Mycobact Dis. 1977 Apr-Jun;45(2):188-9. PubMed PMID: 561764.

5: Holmes IB, Banerjee DK, Hilson GR. Effect of rifampin, clofazimine, and B1912 on the viability of Mycobacterium leprae in established mouse footpad infection. Proc Soc Exp Biol Med. 1976 Apr;151(4):637-41. PubMed PMID: 772686.

6: Banerjee DK, Holmes IB. In vitro and in vivo studies of the action of rifampicin, clofazimine and B1912 on Mycobacterium marinum. Chemotherapy. 1976;22(3-4):242-52. PubMed PMID: 1269290.