B1912

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 584103

CAS#: 24028-59-9

Description: B1912 is an antibacterial agent.


Price and Availability

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Price

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B1912 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 584103
Name: B1912
CAS#: 24028-59-9
Chemical Formula: C30H29ClN4
Exact Mass: 480.2081
Molecular Weight: 481.04
Elemental Analysis: C, 74.91; H, 6.08; Cl, 7.37; N, 11.65


Synonym: B1912; B-1912; B 1912.

IUPAC/Chemical Name: 8-Chloro-3-(cyclohexylmino)-3,5-dihydro-N,5-diphenyl-2-phenazinamine

InChi Key: HTAJQJZZHQMHBK-UHFFFAOYSA-N

InChi Code: InChI=1S/C30H29ClN4/c31-21-16-17-29-27(18-21)34-28-19-25(32-22-10-4-1-5-11-22)26(33-23-12-6-2-7-13-23)20-30(28)35(29)24-14-8-3-9-15-24/h1,3-5,8-11,14-20,23,26,32-33H,2,6-7,12-13H2

SMILES Code: ClC1=CC2=C(C=C1)N(C3=CC=CC=C3)C4=CC(NC5CCCCC5)C(NC6=CC=CC=C6)=CC4=N2


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1: Moynihan R. Canadian media company demands right to publish direct to consumer drug advertising. BMJ. 2009 May 8;338:b1912. doi: 10.1136/bmj.b1912. PubMed PMID: 19429658.

2: Morrison NE. Abortifacient activity of B1912. Int J Lepr Other Mycobact Dis. 1979 Dec;47(4):613-4. PubMed PMID: 122637.

3: Reich CV, de la Cruz E. The effect on pregnant mice of 0.05% B1912 fed in the diet. Int J Lepr Other Mycobact Dis. 1979 Dec;47(4):612-3. PubMed PMID: 122636.

4: Morrison NE, Marley GM. Comparative DNA binding studies with clofazimine and B1912. Int J Lepr Other Mycobact Dis. 1977 Apr-Jun;45(2):188-9. PubMed PMID: 561764.

5: Holmes IB, Banerjee DK, Hilson GR. Effect of rifampin, clofazimine, and B1912 on the viability of Mycobacterium leprae in established mouse footpad infection. Proc Soc Exp Biol Med. 1976 Apr;151(4):637-41. PubMed PMID: 772686.

6: Banerjee DK, Holmes IB. In vitro and in vivo studies of the action of rifampicin, clofazimine and B1912 on Mycobacterium marinum. Chemotherapy. 1976;22(3-4):242-52. PubMed PMID: 1269290.