AZD4635
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 206930

CAS#: 1321514-06-0

Description: AZD-4635, also known as HTL-1071, is an orally available, small molecule adenosine A2A receptor antagonist.


Price and Availability

Size
Price

10mg
USD 150
100mg
USD 750
1g
USD 3250
Size
Price

25mg
USD 250
200mg
USD 1250
2g
USD 5250
Size
Price

50mg
USD 450
500mg
USD 1950
5g
USD 11650

AZD-4635, purity > 98%, is out of stock. New batch is available via customer synthesis. Lead time is about 4-6 weeks. We accept orders now.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 206930
Name: AZD4635
CAS#: 1321514-06-0
Chemical Formula: C15H11ClFN5
Exact Mass: 315.068
Molecular Weight: 315.7364
Elemental Analysis: C, 57.06; H, 3.51; Cl, 11.23; F, 6.02; N, 22.18


Synonym: AZD-4635; AZD 4635; AZD4635; HTL-1071; HTL 1071; HTL1071.

IUPAC/Chemical Name: 6-(2-chloro-6-methylpyridin-4-yl)-5-(4-fluorophenyl)-1,2,4-triazin-3-amine

InChi Key: NCWQLHHDGDXIJN-UHFFFAOYSA-N

InChi Code: InChI=1S/C15H11ClFN5/c1-8-6-10(7-12(16)19-8)14-13(20-15(18)22-21-14)9-2-4-11(17)5-3-9/h2-7H,1H3,(H2,18,20,22)

SMILES Code: NC1=NC(C2=CC=C(F)C=C2)=C(C3=CC(C)=NC(Cl)=C3)N=N1


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Certificate of Analysis:

Safety Data Sheet (MSDS):

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1: Jazayeri A, Andrews SP, Marshall FH. Structurally Enabled Discovery of
Adenosine A(2A) Receptor Antagonists. Chem Rev. 2017 Jan 11;117(1):21-37. doi:
10.1021/acs.chemrev.6b00119. Epub 2016 Jun 22. Review. PubMed PMID: 27333206.

2. http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=9236