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MedKoo CAT#: 561387

CAS#: 1296731-74-2

Description: VU0410150 is a pyrrylarylsulfone containing compound and has been found to be a mGluR4-positive allosteric modulator. VU0410150 has been evaluated as a potential drug for the treatment for Parkinson’s disease.

Price and Availability

Size Price Shipping out time Quantity
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Pricing updated 2020-10-20. Prices are subject to change without notice.

VU0410150 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to to inquire quote.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 561387
Name: VU0410150
CAS#: 1296731-74-2
Chemical Formula: C18H17N3O3S
Exact Mass: 355.0991
Molecular Weight: 355.41
Elemental Analysis: C, 60.83; H, 4.82; N, 11.82; O, 13.50; S, 9.02

Synonym: VU0410150; VU 0410150; VU-0410150;

IUPAC/Chemical Name: N-(1-((3,4-Dimethylphenyl)sulfonyl)-1H-pyrrol-3-yl)picolinamide


InChi Code: InChI=1S/C18H17N3O3S/c1-13-6-7-16(11-14(13)2)25(23,24)21-10-8-15(12-21)20-18(22)17-5-3-4-9-19-17/h3-12H,1-2H3,(H,20,22)

SMILES Code: O=C(NC1=CN(S(=O)(C2=CC=C(C)C(C)=C2)=O)C=C1)C3=NC=CC=C3

Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: Hopkins, C.R.; Lindsley, C.W.; Niswender, C.M. mGluR4-positive allosteric modulation as potential treatment for Parkinson’s disease. Future Med. Chem. 2009, 1, 501–513.

2: Gogliotti, R.D.; Blobaum, A.L.; Morrison, R.M.; Daniels, J.S.; Salovich, J.M.; Cheung, Y.Y.; Rodriguez, A.L.; Loch, M.T.; Conn, P.J.; Lindsley, C.W.; et al. Discovery and characterization of a novel series of N-phenylsulfonyl-1H-pyrrole picolinamides as positive allosteric modulators of the metabotropic glutamate receptor 4 (mGlu4). Bioorg. Med. Chem. Lett. 2016, 26, 2984–2987.