WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 571250
Description: A2315A is an antibiotic.
MedKoo Cat#: 571250
Chemical Formula: C26H37N3O7
Exact Mass: 503.2632
Molecular Weight: 503.6
Elemental Analysis: C, 62.01; H, 7.41; N, 8.34; O, 22.24
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
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Synonym: A2315A; A 2315A; A-2315A; Madumycin II
IUPAC/Chemical Name: (12Z,4R,7R,8R,9Z,14E,16Z,18S,20R)-18,20-dihydroxy-7-isopropyl-4,8,16-trimethyl-6-oxa-3,12-diaza-1(4,2)-oxazolacyclohenicosaphane-9,14,16-triene-2,5,11-trion
InChi Key: SAQNYTQFLPVTNJ-HNSNWRLASA-N
InChi Code: InChI=1S/C26H37N3O7/c1-15(2)24-17(4)8-9-22(32)27-10-6-7-16(3)11-19(30)12-20(31)13-23-29-21(14-35-23)25(33)28-18(5)26(34)36-24/h6-9,11,14-15,17-20,24,30-31H,10,12-13H2,1-5H3,(H,27,32)(H,28,33)/b7-6+,9-8-,16-11-/t17-,18-,19-,20-,24-/m1/s1
SMILES Code: O=C(C1=COC(C[C@H](O)C[C@H](O)/C=C(C)\C=C\CNC(/C=C\[C@@H](C)[C@@H](C(C)C)O2)=O)=N1)N[C@H](C)C2=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 503.6 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Chamberlin JW, Chen S. A2315, new antibiotics produced by Actinoplanes philippinensis. 2. Structure of A2315A. J Antibiot (Tokyo). 1977 Mar;30(3):197-201. PubMed PMID: 405354.
2: Wang ZG, Wang W, Yu SD, Xu ZR. Effects of different activation protocols on preimplantation development, apoptosis and ploidy of bovine parthenogenetic embryos. Anim Reprod Sci. 2008 May;105(3-4):292-301. Epub 2007 Mar 27. PubMed PMID: 17475421.
3: Okumura Y, Sakamoto M, Takei T, Ishikura T, Fukagawa Y. Controlled biosynthesis of neoviridogriseins, new homologues of viridogrisein. IV. In vitro synergism between neoviridogrisein II and the antibiotics of the mikamycin A group. J Antibiot (Tokyo). 1979 Nov;32(11):1130-6. PubMed PMID: 118957.