A 80556

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MedKoo CAT#: 571205

CAS#: 114676-82-3

Description: A 80556 is a fluoroquinolone antibiotic with potent antibacterial activity against gram-positive, gram-negative, and anaerobic organisms.

Price and Availability

Size Price Shipping out time Quantity
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Pricing updated 2020-07-06. Prices are subject to change without notice.

A 80556 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 571205
Name: A 80556
CAS#: 114676-82-3
Chemical Formula: C21H19ClF3N3O3
Exact Mass: 453.1067
Molecular Weight: 453.85
Elemental Analysis: C, 55.58; H, 4.22; Cl, 7.81; F, 12.56; N, 9.26; O, 10.58

Synonym: A 80556; A-80556; A80556

IUPAC/Chemical Name: 3-Quinolinecarboxylic acid, 7-(4-amino-2-methyl-1-pyrrolidinyl)-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-, monohydrochloride, (2S-trans)-


InChi Code: InChI=1S/C21H18F3N3O3.ClH/c1-10-4-12(25)8-26(10)19-7-18-13(6-16(19)24)20(28)14(21(29)30)9-27(18)17-3-2-11(22)5-15(17)23;/h2-3,5-7,9-10,12H,4,8,25H2,1H3,(H,29,30);1H/t10-,12-;/m0./s1

SMILES Code: O=C(C1=CN(C2=CC=C(F)C=C2F)C3=C(C=C(F)C(N4[C@@H](C)C[C@H](N)C4)=C3)C1=O)O.[H]Cl

Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: Clement JJ, Tanaka SK, Alder J, Vojtko C, Beyer J, Hensey D, Ramer N, McDaniel D, Chu DT. In vitro and in vivo evaluations of A-80556, a new fluoroquinolone. Antimicrob Agents Chemother. 1994 May;38(5):1071-8. PubMed PMID: 8067740; PubMed Central PMCID: PMC188152.

2: Destache CJ, Pakiz CB, Stoysich AM. Pharmacodynamics and pharmacokinetics of A-80556 using microdialysis in a Streptococcus pneumoniae meningitis model. J Antimicrob Chemother. 1996 Dec;38(6):977-85. PubMed PMID: 9023645.

3: Yew WW, Piddock LJ, Li MS, Lyon D, Chan CY, Cheng AF. In-vitro activity of quinolones and macrolides against mycobacteria. J Antimicrob Chemother. 1994 Sep;34(3):343-51. PubMed PMID: 7829409.